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Tissue-type plasminogen activator

Summary

UniProt ID

P19637

Gene Symbol

Plat

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P19637
Re-Glyco: P19637

Annotation

Keyword

Cleavage on pair of basic residues
Disulfide bond
EGF-like domain
Glycoprotein
Kringle
Plasminogen activation
Reference proteome
Repeat
Secreted
Serine protease
Signal
Zymogen

Gene Ontology (GO)

Displaying entries **1 - 10** of 11 in total

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GO Term
cell surface
apical part of cell
extracellular space
cytoplasm
secretory granule
postsynapse
serine protease inhibitor complex
perisynaptic space
Schaffer collateral - CA1 synapse
glutamatergic synapse

Displaying entries **1 - 10** of 15 in total

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GO Term
smooth muscle cell migration
prevention of polyspermy
cellular response to dexamethasone stimulus
platelet-derived growth factor receptor signaling pathway
response to cAMP
response to fatty acid
regulation of synaptic plasticity
response to hypoxia
proteolysis
synaptic transmission, glutamatergic

Displaying **all 3** entries
GO Term
serine-type endopeptidase activity
signaling receptor binding
phosphoprotein binding

Annotation information from UniProt.

Sequence

MKGELLCVLLLCGVAFTLPDQGIHRRFRRGARSYRATCRDEQTQTTYQQHQSWLRPMLRGNRVEYCRCNSGLAQCHSVPVRSCSEPRCFNGGTCQQALYFSDFVCQCPDGFVGKRCDIDTRATCFEGQGITYRGTWSTAENGAECINWNSSALSQKPYSARRPNAIKLGLGNHNYCRNPDRDVKPWCYVFKAGKYTTEFCSTPACPKGPTEDCYVGKGVTYRGTHSFTTSKASCLPWNSMILIGKTYTAWRANSQALGLGRHNYCRNPDGDAKPWCHVMKDRKLTWEYCDMSPCSTCGLRQYKQPQFRIKGGLFTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCFVERFPPHHLKVVLGRTYRVVPGEEEQTFEIEKYIVHKEFDDDTYDNDIALLQLRSDSSQCAQESSSVGTACLPDPDVQLPDWTECELSGYGKHEASSPFFSDRLKEAHVRLYPSSRCTSQHLFNKTITSNMLCAGDTRTGGNQDVHDACQGDSGGPLVCMIDKRMTLLGIISWGLGCGQKDVPGIYTKVTNYLNWIQDNMKQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites