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MIRAGE
Tumor necrosis factor receptor superfamily member 1B

Summary
UniProt ID
P20333
Gene Symbol
  • TNFBR
  • TNFR2
  • TNFRSF1B
Gene ID
7133
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P20333
PubChem
P20333
Re-Glyco
P20333
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Apoptosis
  • Cell membrane
  • Direct protein sequencing
  • Disulfide bond
  • Glycoprotein
  • Pharmaceutical
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Secreted
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 9 entries
GO Term
perinuclear region of cytoplasm
varicosity
membrane raft
tumor necrosis factor receptor superfamily complex
specific granule membrane
extracellular region
plasma membrane
membrane
neuronal cell body
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MAPVAVWAALAVGLELWAAAHALPAQVAFTPYAPEPGSTCRLREYYDQTAQMCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACTREQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSNTTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIMTQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPTRNQPQAPGVEASGAGEARASTGSSDSSPGGHGTQVNVTCIVNVCSSSDHSSQCSSQASSTMGDTDSSPSESPKDEQVPFSKEECAFRSQLETPETLLGSTEEKPLPLGVPDAGMKPS
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 9 entries
Position Description PubMed ID GlyTouCan ID Source
30 O-linked (GalNAc...) threonine
171 N-linked (GlcNAc...) asparagine
193 N-linked (GlcNAc...) asparagine
206 O-linked (GalNAc...) threonine
208
221 O-linked (GalNAc...) serine
222 O-linked (GalNAc...) threonine
239
248
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 5 entries
Pathway Name Organism
Interleukin-10 signaling Homo sapiens
Interleukin-4 and Interleukin-13 signaling Homo sapiens
Neutrophil degranulation Homo sapiens
TNFR2 non-canonical NF-kB pathway Homo sapiens
TNFs bind their physiological receptors Homo sapiens
Disease
Displaying entries 1 - 10 of 12 in total
DO ID Disease Name Source
DOID:0080162 lupus nephritis
DOID:0080855 Parkinsonism
DOID:10591 pre-eclampsia
DOID:11394 adult respiratory distress syndrome
DOID:11476 osteoporosis
DOID:289 endometriosis
DOID:2986 IgA glomerulonephritis
DOID:399 tuberculosis
DOID:552 pneumonia
DOID:6000 congestive heart failure
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025