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MIRAGE
Plasminogen activator inhibitor 1
Summary
- UniProt ID
- P20961
- Gene Symbol
-
- Pai1
- Planh1
- Serpine1
- Gene ID
- 24617
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Glycoprotein
- Reference proteome
- Secreted
- Serine protease inhibitor
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| signaling receptor binding |
| protease binding |
| serine-type endopeptidase inhibitor activity |
Sequence
MQMSSALTCLTLGLVLVFGKGFASPLPESHTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERGTAPALRKLSKELMGSWNKNEISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQVDFSEVERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTISVPMMAQNNKFNYTEFTTPDGHEYDILELPYHGETLSMFIAAPFEKDVPLSAITNILDAELIRQWKSNMTRLPRLLILPKFSLETEVDLRGPLEKLGMTDIFSSTQADFTSLSDQEQLSVAQALQKVKIEVNESGTVASSSTAILVSARMAPTEMVLDRSFLFVVRHNPTETILFMGQLMEP
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Dissolution of Fibrin Clot | Rattus norvegicus |
| ECM proteoglycans | Rattus norvegicus |
| Platelet degranulation | Rattus norvegicus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:5199 | ureteral obstruction | |
| DOID:5844 | myocardial infarction | |
| DOID:6432 | pulmonary hypertension | |
| DOID:74 | hematopoietic system disease | |
| DOID:7693 | abdominal aortic aneurysm | |
| DOID:783 | end stage renal disease | |
| DOID:9351 | diabetes mellitus | |
| DOID:9352 | type 2 diabetes mellitus |
