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Mitogen-activated protein kinase 3

Summary

UniProt ID

P21708

Gene Symbol

Mapk3
Erk1
Prkm3

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P21708
PubChem: P21708
The O-GlcNAc Database: P21708

Annotation

Keyword

ATP-binding
Acetylation
Alternative splicing
Apoptosis
Cell cycle
Cell junction
Cytoplasm
Direct protein sequencing
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Ubl conjugation

Gene Ontology (GO)

Displaying entries **41 - 50** of 60 in total

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GO Term
insulin-like growth factor receptor signaling pathway
stress-activated MAPK cascade
interleukin-1-mediated signaling pathway
positive regulation of telomere maintenance via telomerase
response to lipopolysaccharide
regulation of stress-activated MAPK cascade
cellular response to amino acid starvation
ERBB2-ERBB3 signaling pathway
cellular response to tumor necrosis factor
ERK1 and ERK2 cascade

Displaying entries **11 - 16** of 16 in total

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GO Term
protein-containing complex
pseudopodium
glutamatergic synapse
mitochondrion
cytosol
caveola

Displaying **all 10** entries
GO Term
DNA-binding transcription factor binding
identical protein binding
phosphatase binding
phosphotyrosine residue binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase activity
ATP binding
scaffold protein binding
protein serine kinase activity

Annotation information from UniProt.

Sequence

MAAAAAAPGGGGGEPRGTAGVVPVVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMVSSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLPKERLKELIFQETARFQPGAPEAP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **21 - 30** of 41 in total

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Pathway Name	Organism
Negative regulation of MAPK pathway	Rattus norvegicus
Oncogene Induced Senescence	Rattus norvegicus
Oxidative Stress Induced Senescence	Rattus norvegicus
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Rattus norvegicus
RAF-independent MAPK1/3 activation	Rattus norvegicus
RAF/MAP kinase cascade	Rattus norvegicus
RHO GTPases Activate NADPH Oxidases	Rattus norvegicus
RHO GTPases Activate WASPs and WAVEs	Rattus norvegicus
RNA Polymerase I Promoter Opening	Rattus norvegicus
Regulation of HSF1-mediated heat shock response	Rattus norvegicus