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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Fibroblast growth factor receptor 2
Summary
- UniProt ID
- P21802
- Gene Symbol
-
- FGFR2
- BEK
- KGFR
- KSAM
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P21802
- PubChem
- P21802
- The Human Metabolome Database
- HMDBP01305
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Alternative splicing
- Apoptosis
- Cell membrane
- Craniosynostosis
- Cytoplasmic vesicle
- Disease variant
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Heparin-binding
- Immunoglobulin domain
- Intellectual disability
- Lacrimo-auriculo-dento-digital syndrome
- Phosphoprotein
- Proto-oncogene
- Receptor
- Reference proteome
- Repeat
- Secreted
- Signal
- Transmembrane helix
- Tyrosine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| nucleus |
| cytoplasm |
| Golgi apparatus |
| plasma membrane |
| cell cortex |
| membrane |
| cytoplasmic vesicle |
| receptor complex |
| excitatory synapse |
Sequence
MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 40 |
|
|||
| 83 | N-linked (GlcNAc...) asparagine | |||
| 123 | N-linked (GlcNAc...) asparagine |
|
||
| 228 | N-linked (GlcNAc...) asparagine |
|
||
| 241 | N-linked (GlcNAc...) asparagine |
|
||
| 254 |
|
|||
| 265 | N-linked (GlcNAc...) asparagine | |||
| 297 | N-linked (GlcNAc...) asparagine |
|
||
| 318 | N-linked (GlcNAc...) asparagine | |||
| 331 | N-linked (GlcNAc...) asparagine |
|
G43417UB
G86182NS
G62765YT
G10256JP
G40574BA
G59626AS
G80920RR
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activated point mutants of FGFR2 | Homo sapiens |
| Signaling by FGFR2 IIIa TM | Homo sapiens |
| Signaling by FGFR2 amplification mutants | Homo sapiens |
| Signaling by FGFR2 fusions | Homo sapiens |
| Signaling by FGFR2 in disease | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
