Signaling by FGFR2 in disease

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
FRS2Activated FGFR2 mutants:FRS2Activated FGFR2 mutantsADPATPActivated FGFR2 mutants:p-FRS2FGFR2 mutants:p-FRS2:GRB2:SOS1GRB2-1:SOS1GTPp21 RAS:GTPGDPp21 RAS:GDPActivated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1GRB2:GAB1:PIK3R1Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PI3KPIK3CAPIP2PIP3PLC1Activated FGFR2 mutants:PLCG1Activated FGFR2 mutants:p-4Y-PLCG1p-PLCG1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025