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Alpha-2A adrenergic receptor

Summary

UniProt ID

P22909

Gene Symbol

Adra2a

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P22909

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 26 in total

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GO Term
positive regulation of cytokine production
G protein-coupled receptor signaling pathway
female pregnancy
positive regulation of cell migration
glucose homeostasis
platelet activation
cellular response to hormone stimulus
negative regulation of insulin secretion
thermoception
negative regulation of lipid catabolic process

Displaying entries **1 - 10** of 11 in total

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GO Term
cytoplasm
plasma membrane
postsynaptic membrane
neuronal cell body
receptor complex
axon terminus
dopaminergic synapse
glutamatergic synapse
GABA-ergic synapse
presynaptic active zone membrane

Displaying **all 10** entries
GO Term
protein kinase binding
epinephrine binding
norepinephrine binding
alpha-2C adrenergic receptor binding
thioesterase binding
protein homodimerization activity
protein heterodimerization activity
adrenergic receptor activity
alpha2-adrenergic receptor activity
heterotrimeric G-protein binding

Annotation information from UniProt.

Sequence

MFRQEQPLAEGSFAPMGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGTAGAEAEPLPTQLNGAPGEPAPTRPRDGDALDLEESSSSEHAERPQGPGKPERGPRAKGKTKASQVKPGDSLPRRGPGAAGPGASGSGQGEERAGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPYQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
25	N-linked (GlcNAc...) asparagine			UniProt
29	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Adrenaline signalling through Alpha-2 adrenergic receptor	Rattus norvegicus
Adrenaline,noradrenaline inhibits insulin secretion	Rattus norvegicus
Adrenoceptors	Rattus norvegicus
G alpha (i) signalling events	Rattus norvegicus
G alpha (z) signalling events	Rattus norvegicus
Surfactant metabolism	Rattus norvegicus