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Alpha-2A adrenergic receptor

Summary

UniProt ID

P22909

Gene Symbol

Adra2a

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P22909

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Methylation
Palmitate
Phosphoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying entries **21 - 26** of 26 in total

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GO Term
adrenergic receptor signaling pathway
positive regulation of MAPK cascade
negative regulation of uterine smooth muscle contraction
adenylate cyclase-activating adrenergic receptor signaling pathway
adenylate cyclase-inhibiting adrenergic receptor signaling pathway
phospholipase C-activating adrenergic receptor signaling pathway

Displaying entries **1 - 10** of 11 in total

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GO Term
presynaptic active zone membrane
postsynaptic density membrane
cytoplasm
plasma membrane
postsynaptic membrane
neuronal cell body
receptor complex
axon terminus
dopaminergic synapse
glutamatergic synapse

Displaying **all 10** entries
GO Term
alpha-2C adrenergic receptor binding
thioesterase binding
protein homodimerization activity
protein heterodimerization activity
adrenergic receptor activity
alpha2-adrenergic receptor activity
heterotrimeric G-protein binding
protein kinase binding
epinephrine binding
norepinephrine binding

Annotation information from UniProt.

Sequence

MFRQEQPLAEGSFAPMGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGTAGAEAEPLPTQLNGAPGEPAPTRPRDGDALDLEESSSSEHAERPQGPGKPERGPRAKGKTKASQVKPGDSLPRRGPGAAGPGASGSGQGEERAGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPYQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
25	N-linked (GlcNAc...) asparagine			UniProt
29	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Adrenaline signalling through Alpha-2 adrenergic receptor	Rattus norvegicus
Adrenaline,noradrenaline inhibits insulin secretion	Rattus norvegicus
Adrenoceptors	Rattus norvegicus
G alpha (i) signalling events	Rattus norvegicus
G alpha (z) signalling events	Rattus norvegicus
Surfactant metabolism	Rattus norvegicus