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Brain-derived neurotrophic factor

Summary

UniProt ID

P23363

Gene Symbol

Bdnf

Organism

Rattus norvegicus (Norway rat)

External Links

PubChem: P23363

Annotation

Keyword

Cleavage on pair of basic residues
Disulfide bond
Glycoprotein
Growth factor
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying entries **31 - 40** of 89 in total

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GO Term
positive regulation of neuron differentiation
negative regulation of striated muscle tissue development
regulation of retinal cell programmed cell death
inner ear development
modulation of chemical synaptic transmission
neuron apoptotic process
response to electrical stimulus
positive regulation of synapse assembly
taste bud development
cellular response to norepinephrine stimulus

Displaying entries **1 - 10** of 17 in total

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GO Term
extracellular region
extracellular space
cytoplasm
secretory granule
axon
cytoplasmic vesicle
terminal bouton
dendrite
neuronal cell body
postsynapse

Displaying **all 3** entries
GO Term
nerve growth factor receptor binding
neurotrophin TRKB receptor binding
growth factor activity

Annotation information from UniProt.

Sequence

MTILFLTMVISYFGCMKAAPMKEANVHGQGNLAYPAVRTHGTLESVNGPRAGSRGLTTTSLADTFEHVIEELLDEDQKVRPNEENHKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
123	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Activated NTRK2 signals through FRS2 and FRS3	Rattus norvegicus
Activated NTRK2 signals through PLCG1	Rattus norvegicus
NTRK2 activates RAC1	Rattus norvegicus