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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
Summary
- UniProt ID
- P26439
- Gene Symbol
-
- HSD3B2
- HSDB3B
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P26439
- PubChem
- P26439
- SwissLipids
- The Human Metabolome Database
- HMDBP04404
- The O-GlcNAc Database
- P26439
Annotation
- Keyword
-
- Alternative splicing
- Congenital adrenal hyperplasia
- Disease variant
- Endoplasmic reticulum
- Isomerase
- Lipid metabolism
- Mitochondrion
- Multifunctional enzyme
- NAD
- Oxidoreductase
- Reference proteome
- Steroidogenesis
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| steroid biosynthetic process |
| C21-steroid hormone metabolic process |
| hippocampus development |
| response to corticosterone |
| androgen biosynthetic process |
| GO Term |
|---|
| smooth endoplasmic reticulum membrane |
| intercellular bridge |
| mitochondrial inner membrane |
| mitochondrial membrane |
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| mitochondrial intermembrane space |
| nucleolus |
| cytoplasm |
| membrane |
Sequence
MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 263 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Androgen biosynthesis | Homo sapiens |
| Glucocorticoid biosynthesis | Homo sapiens |
| Mineralocorticoid biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12698 | gynecomastia | |
| DOID:12700 | hyperprolactinemia | |
| DOID:1380 | endometrial cancer | |
| DOID:1470 | major depressive disorder | |
| DOID:1595 | melancholic depression | |
| DOID:1596 | depressive disorder | |
| DOID:1923 | disorder of sexual development | |
| DOID:2048 | autoimmune hepatitis | |
| DOID:2237 | hepatitis | |
| DOID:2848 | obsolete melancholia |
