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V-type proton ATPase 16 kDa proteolipid subunit c

Summary

UniProt ID

P27449

Gene Symbol

ATP6C
ATP6L
ATP6V0C
ATPL

Gene ID

527

Organism

Homo sapiens (human)

External Links

PubChem: P27449
The Human Metabolome Database: HMDBP01481
The O-GlcNAc Database: P27449
RaftProt: P27449
Re-Glyco: P27449

Annotation

Keyword

3D-structure
Cytoplasmic vesicle
Disease variant
Epilepsy
Host-virus interaction
Hydrogen ion transport
Reference proteome
Synapse
Transmembrane helix
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

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GO Term
phagocytic vesicle membrane
proton-transporting V-type ATPase complex
vacuolar proton-transporting V-type ATPase, V0 domain
azurophil granule membrane
plasma membrane
membrane
Golgi membrane
lysosomal membrane
focal adhesion
endosome membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 9** entries
GO Term
positive regulation of Wnt signaling pathway
endosomal lumen acidification
Golgi lumen acidification
vacuolar acidification
intracellular pH reduction
synaptic vesicle lumen acidification
proton transmembrane transport
lysosomal lumen acidification
regulation of macroautophagy

Displaying **all 3** entries
GO Term
ubiquitin protein ligase binding
proton-transporting ATP synthase activity, rotational mechanism
proton-transporting ATPase activity, rotational mechanism

Annotation information from UniProt.

Sequence

MSESKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIYGLVVAVLIANSLNDDISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
20	G49108TO	The O-GlcNAc Database
26	G49108TO	The O-GlcNAc Database
39	G49108TO	The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Amino acids regulate mTORC1	Homo sapiens
Insulin receptor recycling	Homo sapiens
Ion channel transport	Homo sapiens
Neutrophil degranulation	Homo sapiens
ROS and RNS production in phagocytes	Homo sapiens
Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy	Homo sapiens
Transferrin endocytosis and recycling	Homo sapiens