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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
Summary
- UniProt ID
- P28331
- Gene Symbol
-
- NDUFS1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 2Fe-2S
- 3D-structure
- 4Fe-4S
- Acetylation
- Alternative splicing
- Direct protein sequencing
- Disease variant
- Mitochondrion inner membrane
- NAD
- Oxidoreductase
- Primary mitochondrial disease
- Reference proteome
- Respiratory chain
- Transit peptide
- Translocase
- Ubiquinone
- Gene Ontology (GO)
| GO Term |
|---|
| mitochondrion |
| mitochondrial inner membrane |
| mitochondrial respiratory chain complex I |
| mitochondrial matrix |
| mitochondrial intermembrane space |
| GO Term |
|---|
| metal ion binding |
| 2 iron, 2 sulfur cluster binding |
| 4 iron, 4 sulfur cluster binding |
| electron transfer activity |
| NADH dehydrogenase (ubiquinone) activity |
Sequence
MLRIPVRKALVGLSKSPKGCVRTTATAASNLIEVFVDGQSVMVEPGTTVLQACEKVGMQIPRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSKKAREGVMEFLLANHPLDCPICDQGGECDLQDQSMMFGNDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCTRCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTARPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQRLTEPMVRNEKGLLTYTSWEDALSRVAGMLQSFQGKDVAAIAGGLVDAEALVALKDLLNRVDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVVLLVGTNPRFEAPLFNARIRKSWLHNDLKVALIGSPVDLTYTYDHLGDSPKILQDIASGSHPFSQVLKEAKKPMVVLGSSALQRNDGAAILAAVSSIAQKIRMTSGVTGDWKVMNILHRIASQVAALDLGYKPGVEAIRKNPPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTEGRAQQTKVAVTPPGLAREDWKIIRALSEIAGMTLPYDTLDQVRNRLEEVSPNLVRYDDIEGANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQAVEEPSIC
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 259 |
|
|||
| 264 |
|
|||
| 265 |
|
|||
| 318 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Complex I biogenesis | Homo sapiens |
| Mitochondrial protein degradation | Homo sapiens |
| Respiratory electron transport | Homo sapiens |
