Complex I biogenesis

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
NUBPLNUBPL:4Fe-4S4Fe-4SNDUF:4Fe-4S subunitsNDUF subunitsFMNNDUFV1NDUFV2:4Fe-4SNDUFV1:4Fe-4S:FMNNDUFV2NDUFS7:4Fe-4SIP subcomplexNDUFS8:2x4Fe-4SNDUFAF7:NDUFS2:2x4Fe-4SNDUFA9:FADNDUFS3NDUFAF3Intermediate 1TIMMDC1NDUFAF4HP subcomplexIntermediate 2NDUFAF6315kDa subcomplexNDUFAF5MT-ND1MCIA complex370 kDa subcomplexCOA1:MT-ND2TMEM186:MT-ND3NDUFB6MT-ND6550kDa complexMT-ND4 mRNAMT-ND4815kDa complexMT-ND5FP subcomplexNDUFS4NDUFAF2NDUFA12NDUFS1:2x4Fe-4SNDUFS6NDUFV3NDUFS5980kDa complexComplex INDUFAF7
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025