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MIRAGE
Neuroendocrine convertase 1

Summary
UniProt ID
P28840
Gene Symbol
  • Bdp
  • Nec-1
  • Nec1
  • Pcsk1
Gene ID
25204
Organism
Rattus norvegicus (Norway rat)
PubChem
P28840
Re-Glyco
P28840
Annotation
Keyword
  • Calcium
  • Cleavage on pair of basic residues
  • Cytoplasmic vesicle
  • Disulfide bond
  • Glycoprotein
  • Reference proteome
  • Serine protease
  • Signal
  • Zymogen
Gene Ontology (GO)
Displaying entries 1 - 10 of 12 in total
GO Term
secretory granule lumen
extracellular space
membrane
secretory granule
dendrite
neuron projection
neuronal cell body
trans-Golgi network
perinuclear region of cytoplasm
transport vesicle
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MKQRGWTLQCTAFTLFCVWCALNSVKAKRQFVNEWAAEIHGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERRKRSVPRDSALNLFNDPMWNQQWYLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECIIKDNNFEPRALKANGEVIVEIPTRACEGQENAINSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKVTDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEEKPTQNSLNGNLLVPKNSSSSSVEDRRDEQVQGAPSKAMLRLLQSAFSKNTPSKQSSKIPSAKLSVPYEGLYEALEKLNKPSQLEDSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEKN
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 3 entries
Position Description PubMed ID GlyTouCan ID Source
173 N-linked (GlcNAc...) asparagine
401 N-linked (GlcNAc...) asparagine
645 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Peptide hormone biosynthesis Rattus norvegicus
Synthesis, secretion, and deacylation of Ghrelin Rattus norvegicus
Disease
Displaying all 2 entries
DO ID Disease Name Source
DOID:4195 hyperglycemia
DOID:9352 type 2 diabetes mellitus
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025