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M-phase inducer phosphatase 1

Summary

UniProt ID

P30304

Gene Symbol

CDC25A

Organism

Homo sapiens (human)

External Links

GlyGen: P30304
PubChem: P30304
The Human Metabolome Database: HMDBP08919
The O-GlcNAc Database: P30304

Annotation

Keyword

3D-structure
Alternative splicing
Mitosis
Phosphoprotein
Protein phosphatase
Reference proteome
Ubl conjugation

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
cell population proliferation
response to radiation
cell division
positive regulation of DNA replication
cellular response to UV
regulation of cyclin-dependent protein serine/threonine kinase activity
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
positive regulation of G2/M transition of mitotic cell cycle
positive regulation of G2/MI transition of meiotic cell cycle

Displaying **all 4** entries
GO Term
cytosol
nucleoplasm
nucleus
cytoplasm

Displaying **all 4** entries
GO Term
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
protein kinase binding
protein-folding chaperone binding

Annotation information from UniProt.

Sequence

MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYEQPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 3** entries
Position	GlyTouCan ID	Source
34	G49108TO	GlyGen The O-GlcNAc Database
48	G49108TO	GlyGen The O-GlcNAc Database
69	G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
Activation of ATR in response to replication stress	Homo sapiens
Cyclin A/B1/B2 associated events during G2/M transition	Homo sapiens
Cyclin A:Cdk2-associated events at S phase entry	Homo sapiens
Cyclin E associated events during G1/S transition	Homo sapiens
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	Homo sapiens
Polo-like kinase mediated events	Homo sapiens
Transcription of E2F targets under negative control by DREAM complex	Homo sapiens
Ub-specific processing proteases	Homo sapiens
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	Homo sapiens