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MIRAGE
72 kDa type IV collagenase
Summary
- UniProt ID
- P33436
- Gene Symbol
-
- Mmp2
- Gene ID
- 81686
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Angiogenesis
- Autocatalytic cleavage
- Calcium
- Collagen degradation
- Disulfide bond
- Extracellular matrix
- Glycoprotein
- Membrane
- Metal-binding
- Metalloprotease
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular space |
| nucleus |
| plasma membrane |
| sarcomere |
| extracellular matrix |
| GO Term |
|---|
| angiogenesis |
| response to hypoxia |
| intramembranous ossification |
| proteolysis |
| negative regulation of cell adhesion |
| female pregnancy |
| parturition |
| response to mechanical stimulus |
| cell migration |
| extracellular matrix organization |
Sequence
MEARLVWGVLVGPLRVLCVLCCLLGHAIAAPSPIIKFPGDVSPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNGDGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSNDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFSGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Rattus norvegicus |
| Collagen degradation | Rattus norvegicus |
| Degradation of the extracellular matrix | Rattus norvegicus |
| EPH-ephrin mediated repulsion of cells | Rattus norvegicus |
| Extra-nuclear estrogen signaling | Rattus norvegicus |
| Regulation of IGF Activity by IGFBP | Rattus norvegicus |
