72 kDa type IV collagenase

Summary
UniProt ID
P33436
Gene Symbol
  • Mmp2
Organism
Rattus norvegicus (Norway rat)
PubChem
P33436
Annotation
Keyword
  • Angiogenesis
  • Autocatalytic cleavage
  • Calcium
  • Collagen degradation
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Membrane
  • Metal-binding
  • Metalloprotease
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Gene Ontology (GO)
Sequence
MEARLVWGVLVGPLRVLCVLCCLLGHAIAAPSPIIKFPGDVSPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARALKVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGREYSSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNGDGQPCKFPFRFQGTSYNSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKVWCATTTNYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSNDDIKGIQELYGPSPDADTDTGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPTGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWVYSASTLERGYPKPLTSLGLPPDVQQVDAAFNWSKNKKTYIFSGDKFWRYNEVKKKMDPGFPKLIADSWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
Glycosylation Sites
Displaying all 2 entries
Position Description PubMed ID GlyTouCan ID Source
575 N-linked (GlcNAc...) asparagine
644 N-linked (GlcNAc...) asparagine
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Activation of Matrix Metalloproteinases Rattus norvegicus
Collagen degradation Rattus norvegicus
Degradation of the extracellular matrix Rattus norvegicus
EPH-ephrin mediated repulsion of cells Rattus norvegicus
Extra-nuclear estrogen signaling Rattus norvegicus
Regulation of IGF Activity by IGFBP Rattus norvegicus

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024