Degradation of the extracellular matrix

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ElastinCleaved elastinFibrillin-1Cleaved fibrillin-1Fibronectin matrixCleaved fibronectin matrixCleaved fibronectin matrix Ala(271)/Val(272)H2OACAN(376-2415)ACANACAN(17-375)BcanBcanBcanBcanBcanDcnDcnDcnCDH1(155-882):Ca2+ dimerE-cadherin strand dimer fragment 701-882E-cadherin strand dimer fragment 155-700MMP1, 3, 13, (2, 7-12, 19)Alpha 2-macroglobulin:MMP1, 3, 13, (2, 7-12, 19)A2M tetramerCD44CD44:MMP2, MMP7, MMP9MMP2, MMP7, MMP9BsgBSG:MMP1(100-469)B5DFD5Spp1Spp1Spp1substrate protein for calpainscalpain-cleaved proteinOptcOptcOptcOptcOptcOptcOptcScube3Scube3Scube3SCUBE1,SCUBE3SCUBE1,SCUBE3 polymer, SCUBE3 polymer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 3 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000052 P07897 Aggrecan core protein view
GL_000110 P55068 Brevican core protein view
GL_004560 P26453 Basigin view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025