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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Thrombospondin-1
Summary
- UniProt ID
- P35441
- Gene Symbol
-
- Thbs1
- Tsp1
- Organism
- Mus musculus (house mouse)
External Links
- GlycoProtDB
- GPDB0003587
- GlyConnect
- GlyGen
- P35441
- PubChem
- P35441
- RaftProt
- P35441
Annotation
- Keyword
-
- Angiogenesis
- Apoptosis
- Calcium
- Cell adhesion
- Direct protein sequencing
- Disulfide bond
- EGF-like domain
- Endoplasmic reticulum
- Extracellular matrix
- Glycoprotein
- Heparin-binding
- Inflammatory response
- Reference proteome
- Repeat
- Sarcoplasmic reticulum
- Signal
- Unfolded protein response
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of cell-substrate adhesion |
| positive regulation of transforming growth factor beta receptor signaling pathway |
| GO Term |
|---|
| cell surface |
| extracellular space |
| extracellular matrix |
| collagen-containing extracellular matrix |
| sarcoplasmic reticulum |
| endoplasmic reticulum |
| GO Term |
|---|
| calcium ion binding |
| heparin binding |
| transforming growth factor beta binding |
| extracellular matrix binding |
| fibronectin binding |
Sequence
MELLRGLGVLFLLHMCGSNRIPESGGDNGVFDIFELIGGARRGPGRRLVKGQDLSSPAFRIENANLIPAVPDDKFQDLLDAVWADKGFIFLASLRQMKKTRGTLLAVERKDNTGQIFSVVSNGKAGTLDLSLSLPGKQQVVSVEEALLATGQWKSITLFVQEDRAQLYIDCDKMESAELDVPIQSIFTRDLASVARLRVAKGDVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTNVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGLSCDELSSMVLELKGLRTIVTTLQDSIRKVTEENRELVSELKRPPLCFHNGVQYKNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQRRSRLCNNPTPQFGGKDCVGDVTENQVCNKQDCPIDGCLSNPCFAGAKCTSYPDGSWKCGACPPGYSGNGIQCKDVDECKEVPDACFNHNGEHRCKNTDPGYNCLPCPPRFTGSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDKNGEGDACAVDIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDLIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDNVPDIDDICPENFDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGYIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDMKYECRDS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 248 | N-linked (GlcNAc...) asparagine | |||
| 360 | N-linked (GlcNAc...) asparagine |
|
||
| 385 | C-linked (Man) tryptophan |
|
||
| 438 | C-linked (Man) tryptophan |
|
||
| 441 | C-linked (Man) tryptophan |
|
||
| 450 | O-linked (Fuc...) threonine |
|
||
| 498 | C-linked (Man) tryptophan |
|
||
| 507 | O-linked (Fuc...) threonine |
|
||
| 553 |
|
|
||
| 708 | N-linked (GlcNAc...) asparagine |
|
G90659AW
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Integrin cell surface interactions | Mus musculus |
| O-glycosylation of TSR domain-containing proteins | Mus musculus |
| Platelet degranulation | Mus musculus |
| Signaling by PDGF | Mus musculus |
