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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
Summary
- UniProt ID
- P35486
- Gene Symbol
-
- Pdha1
- Pdha-1
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Acetylation
- Direct protein sequencing
- Glucose metabolism
- Mitochondrion
- Oxidoreductase
- Phosphoprotein
- Pyruvate
- Reference proteome
- Thiamine pyrophosphate
- Transit peptide
- Tricarboxylic acid cycle
- Gene Ontology (GO)
| GO Term |
|---|
| glucose metabolic process |
| tricarboxylic acid cycle |
| acetyl-CoA biosynthetic process from pyruvate |
| GO Term |
|---|
| nucleolus |
| myelin sheath |
| catalytic complex |
| mitochondrion |
| mitochondrial pyruvate dehydrogenase complex |
| pyruvate dehydrogenase complex |
| GO Term |
|---|
| pyruvate dehydrogenase activity |
| pyruvate dehydrogenase (acetyl-transferring) activity |
| pyruvate dehydrogenase (NAD+) activity |
Sequence
MRKMLAAVSRVLAGSAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Mitochondrial protein degradation | Mus musculus |
| PDH complex synthesizes acetyl-CoA from PYR | Mus musculus |
| Regulation of pyruvate dehydrogenase (PDH) complex | Mus musculus |
| Signaling by Retinoic Acid | Mus musculus |
