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MIRAGE
Dual specificity mitogen-activated protein kinase kinase 2
Summary
- UniProt ID
- P36506
- Gene Symbol
-
- Map2k2
- Mek2
- Mkk2
- Prkmk2
- Gene ID
- 58960
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Acetylation
- Cytoplasm
- Magnesium
- Membrane
- Metal-binding
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| perinuclear region of cytoplasm |
| microtubule |
| focal adhesion |
| cytoplasmic side of plasma membrane |
| GO Term |
|---|
| myelination |
| positive regulation of cell motility |
| positive regulation of DNA-templated transcription |
| GO Term |
|---|
| protein serine/threonine/tyrosine kinase activity |
| PDZ domain binding |
| histone H2AXY142 kinase activity |
| metal ion binding |
Sequence
MLARRKPVLPALTINPTIAEGPSPTSEGASEAHLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLTNHAFIKRSEGEDVDFAGWLCRTLRLKQPSTPTRTAV
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 25 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Frs2-mediated activation | Rattus norvegicus |
| MAP2K and MAPK activation | Rattus norvegicus |
| MAPK1 (ERK2) activation | Rattus norvegicus |
| Negative feedback regulation of MAPK pathway | Rattus norvegicus |
| RAF activation | Rattus norvegicus |
| Signal transduction by L1 | Rattus norvegicus |
