Dual specificity mitogen-activated protein kinase kinase 2

Summary
UniProt ID
P36506
Gene Symbol
  • Map2k2
  • Mek2
  • Mkk2
  • Prkmk2
Organism
Rattus norvegicus (Norway rat)
External Links
GlyGen
P36506
PubChem
P36506
The O-GlcNAc Database
P36506
Annotation
Keyword
  • ATP-binding
  • Acetylation
  • Cytoplasm
  • Magnesium
  • Membrane
  • Metal-binding
  • Phosphoprotein
  • Reference proteome
  • Serine/threonine-protein kinase
  • Tyrosine-protein kinase
Gene Ontology (GO)
Sequence
MLARRKPVLPALTINPTIAEGPSPTSEGASEAHLVDLQKKLEELDLDEQQRKRLEAFLTQKAKVGELKDDDFERISELGAGNGGVVTKARHRPSGLIMARKLIHLEIKPAVRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKEAKRIPEDILGKVSIAVLRGLAYLREKHQIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVELAIGRYPIPPPDAKELEASFGRPVVDGADGEPHSVSPRPRPPGRPISGHGMDSRPAMAIFELLDYIVNEPPPKLPSGVFSSDFQEFVNKCLIKNPAERADLKLLTNHAFIKRSEGEDVDFAGWLCRTLRLKQPSTPTRTAV
Glycosylation Sites
Displaying 1 entry
Position Description PubMed ID GlyTouCan ID Source
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 6 entries
Pathway Name Organism
Frs2-mediated activation Rattus norvegicus
MAP2K and MAPK activation Rattus norvegicus
MAPK1 (ERK2) activation Rattus norvegicus
Negative feedback regulation of MAPK pathway Rattus norvegicus
RAF activation Rattus norvegicus
Signal transduction by L1 Rattus norvegicus

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International Collaboration

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024