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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Summary
- UniProt ID
- P42338
- Gene Symbol
-
- PIK3CB
- PIK3C1
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P42338
- PubChem
- P42338
- The Human Metabolome Database
- HMDBP01208
- The O-GlcNAc Database
- P42338
Annotation
- Keyword
-
- ATP-binding
- Autophagy
- Cell adhesion
- Cytoplasm
- Endocytosis
- Kinase
- Lipid metabolism
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
Sequence
MCFSFIMPPAMADILDIWAVDSQIASDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLWKQVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGEKLDSKIGVLIGKGLHEFDSLKDPEVNEFRRKMRKFSEEKILSLVGLSWMDWLKQTYPPEHEPSIPENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKVNELAIQKRLTIHGKEDEVSPYDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRALPHFILVECCKIKKMYEQEMIAIEAAINRNSSNLPLPLPPKKTRIISHVWENNNPFQIVLVKGNKLNTEETVKVHVRAGLFHGTELLCKTIVSSEVSGKNDHIWNEPLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTINPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRTGDIILHSWSSFPDELEEMLNPMGTVQTNPYTENATALHVKFPENKKQPYYYPPFDKIIEKAAEIASSDSANVSSRGGKKFLPVLKEILDRDPLSQLCENEMDLIWTLRQDCREIFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPKLPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFLLERALGNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLKTLNSLIKLNAVKLNRAKGKEAMHTCLKQSAYREALSDLQSPLNPCVILSELYVEKCKYMDSKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYGCLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEEFTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFILTYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKDIQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 478 |
|
|||
| 481 |
|
|||
| 485 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Signaling by ALK fusions and activated point mutants | Homo sapiens |
| Signaling by CSF1 (M-CSF) in myeloid cells | Homo sapiens |
| Signaling by LTK | Homo sapiens |
| Signaling by LTK in cancer | Homo sapiens |
| Signaling by PDGFRA extracellular domain mutants | Homo sapiens |
| Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants | Homo sapiens |
| Synthesis of PIPs at the plasma membrane | Homo sapiens |
| Tie2 Signaling | Homo sapiens |
| VEGFA-VEGFR2 Pathway | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2043 | hepatitis B | |
| DOID:205 | hyperostosis | |
| DOID:2095 | sweat gland cancer | |
| DOID:2129 | atypical teratoid rhabdoid tumor | |
| DOID:2154 | nephroblastoma | |
| DOID:219 | colon cancer | |
| DOID:2224 | essential thrombocythemia | |
| DOID:2226 | myeloproliferative neoplasm | |
| DOID:2237 | hepatitis | |
| DOID:224 | transient cerebral ischemia |
