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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Caspase-3
Summary
- UniProt ID
- P42574
- Gene Symbol
-
- CASP3
- CPP32
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Apoptosis
- Cytoplasm
- Direct protein sequencing
- Phosphoprotein
- Reference proteome
- S-nitrosylation
- Thiol protease
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| nucleus |
| cytoplasm |
| neuronal cell body |
| death-inducing signaling complex |
| cytosol |
| nucleoplasm |
| GO Term |
|---|
| phospholipase A2 activator activity |
| cysteine-type endopeptidase activity involved in apoptotic process |
Sequence
MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of caspases through apoptosome-mediated cleavage | Homo sapiens |
| Apoptosis induced DNA fragmentation | Homo sapiens |
| Apoptotic cleavage of cell adhesion proteins | Homo sapiens |
| Apoptotic cleavage of cellular proteins | Homo sapiens |
| Caspase-mediated cleavage of cytoskeletal proteins | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
| Ligand-independent caspase activation via DCC | Homo sapiens |
| NADE modulates death signalling | Homo sapiens |
| Other interleukin signaling | Homo sapiens |
| Pyroptosis | Homo sapiens |
