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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Collagenase 3
Summary
- UniProt ID
- P45452
- Gene Symbol
-
- MMP13
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P45452
- PubChem
- P45452
- The Human Metabolome Database
- HMDBP02183
- The O-GlcNAc Database
- P45452
Annotation
- Keyword
-
- 3D-structure
- Calcium
- Collagen degradation
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Dwarfism
- Extracellular matrix
- Glycoprotein
- Metal-binding
- Metalloprotease
- Phosphoprotein
- Reference proteome
- Repeat
- Signal
- Zinc
- Zymogen
- Gene Ontology (GO)
| GO Term |
|---|
| extracellular region |
| extracellular space |
| extracellular matrix |
| GO Term |
|---|
| serine-type endopeptidase activity |
| calcium ion binding |
| zinc ion binding |
| endopeptidase activity |
| metalloendopeptidase activity |
| collagen binding |
Sequence
MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENAASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGETMIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGYDILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLIEEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of Matrix Metalloproteinases | Homo sapiens |
| Assembly of collagen fibrils and other multimeric structures | Homo sapiens |
| Collagen degradation | Homo sapiens |
| Degradation of the extracellular matrix | Homo sapiens |
| RUNX2 regulates genes involved in cell migration | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
