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MIRAGE
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

Summary
UniProt ID
P46977
Gene Symbol
  • ITM1
  • STT3A
  • TMC
Gene ID
3703
Organism
Homo sapiens (human)
GlyConnect
GlyGen
P46977
PubChem
P46977
The Human Metabolome Database
HMDBP02781
The O-GlcNAc Database
P46977
RaftProt
P46977
O-GlcNAcAtlas
P46977
Re-Glyco
P46977
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Congenital disorder of glycosylation
  • Disease variant
  • Endoplasmic reticulum
  • Glycoprotein
  • Glycosyltransferase
  • Magnesium
  • Manganese
  • Metal-binding
  • Reference proteome
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 3 entries
GO Term
membrane
endoplasmic reticulum membrane
oligosaccharyltransferase complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Annotation information from UniProt.
Sequence
MTKFGFLRLSYEKQDTLLKLLILSMAAVLSFSTRLFAVLRFESVIHEFDPYFNYRTTRFLAEEGFYKFHNWFDDRAWYPLGRIIGGTIYPGLMITSAAIYHVLHFFHITIDIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAGSYDNEGIAIFCMLLTYYMWIKAVKTGSICWAAKCALAYFYMVSSWGGYVFLINLIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQISFVGFQPVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISPWTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLLVFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKNEVASGMILVMAFFLITYTFHSTWVTSEAYSSPSIVLSARGGDGSRIIFDDFREAYYWLRHNTPEDAKVMSWWDYGYQITAMANRTILVDNNTWNNTHISRVGQAMASTEEKAYEIMRELDVSYVLVIFGGLTGYSSDDINKFLWMVRIGGSTDTGKHIKENDYYTPTGEFRVDREGSPVLLNCLMYKMCYYRFGQVYTEAKRPPGFDRVRNAEIGNKDFELDVLEEAYTTEHWLVRIYKVKDLDNRGLSRT
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 10 entries
Position Description PubMed ID GlyTouCan ID Source
124
537 N-linked (GlcNAc...) asparagine
539
544 N-linked (GlcNAc...) asparagine
545
546
548 N-linked (GlcNAc...) (high mannose) asparagine
549
550
553
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Asparagine N-linked glycosylation Homo sapiens
Maturation of spike protein Homo sapiens
Disease
Displaying 1 entry
DO ID Disease Name Source
DOID:0080572 congenital disorder of glycosylation Iw
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025