Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
Tumor necrosis factor ligand superfamily member 6
Summary
- UniProt ID
- P48023
- Gene Symbol
-
- APT1LG1
- CD95L
- FASL
- FASLG
- TNFSF6
- Gene ID
- 356
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Apoptosis
- Cell membrane
- Cytokine
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Lysosome
- Nucleus
- Reference proteome
- Repressor
- Secreted
- Signal-anchor
- Transcription regulation
- Transmembrane helix
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| signaling receptor binding |
| death receptor binding |
| cytokine activity |
| tumor necrosis factor receptor binding |
Sequence
MQQPFNYPYPQIYWVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPPPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQMHTASSLEKQIGHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL
Glycosylation Sites
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CASP8 activity is inhibited | Homo sapiens |
| Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | Homo sapiens |
| Dimerization of procaspase-8 | Homo sapiens |
| FOXO-mediated transcription of cell death genes | Homo sapiens |
| FasL/ CD95L signaling | Homo sapiens |
| Interleukin-4 and Interleukin-13 signaling | Homo sapiens |
| Ligand-dependent caspase activation | Homo sapiens |
| RIPK1-mediated regulated necrosis | Homo sapiens |
| Regulation by c-FLIP | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10591 | pre-eclampsia | |
| DOID:11054 | urinary bladder cancer | |
| DOID:13133 | HELLP syndrome | |
| DOID:1324 | lung cancer | |
| DOID:1793 | pancreatic cancer | |
| DOID:1909 | melanoma | |
| DOID:2377 | multiple sclerosis | |
| DOID:3587 | pancreatic ductal carcinoma | |
| DOID:4947 | cholangiocarcinoma | |
| DOID:6688 | autoimmune lymphoproliferative syndrome |
