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Leptin receptor

Summary

UniProt ID

P48357

Gene Symbol

LEPR
DB
OBR

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011694

GlyConnect

1954

GlyGen

P48357

PubChem

P48357

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Obesity
Phosphoprotein
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 25 in total

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GO Term
angiogenesis
positive regulation of protein phosphorylation
glycogen metabolic process
gluconeogenesis
energy reserve metabolic process
phagocytosis
cell surface receptor signaling pathway
multicellular organism development
cytokine-mediated signaling pathway
sexual reproduction

Displaying **all 4** entries
GO Term
extracellular region
receptor complex
basolateral plasma membrane
external side of plasma membrane

Displaying **all 5** entries
GO Term
transmembrane signaling receptor activity
cytokine receptor activity
cytokine binding
identical protein binding
leptin receptor activity

Annotation information from UniProt.

Sequence

MICQKFCVVLLHWEFIYVITAFNLSYPITPWRFKLSCMPPNSTYDYFLLPAGLSKNTSNSNGHYETAVEPKFNSSGTHFSNLSKTTFHCCFRSEQDRNCSLCADNIEGKTFVSTVNSLVFQQIDANWNIQCWLKGDLKLFICYVESLFKNLFRNYNYKVHLLYVLPEVLEDSPLVPQKGSFQMVHCNCSVHECCECLVPVPTAKLNDTLLMCLKITSGGVIFQSPLMSVQPINMVKPDPPLGLHMEITDDGNLKISWSSPPLVPFPLQYQVKYSENSTTVIREADKIVSATSLLVDSILPGSSYEVQVRGKRLDGPGIWSDWSTPRVFTTQDVIYFPPKILTSVGSNVSFHCIYKKENKIVPSKEIVWWMNLAEKIPQSQYDVVSDHVSKVTFFNLNETKPRGKFTYDAVYCCNEHECHHRYAELYVIDVNINISCETDGYLTKMTCRWSTSTIQSLAESTLQLRYHRSSLYCSDIPSIHPISEPKDCYLQSDGFYECIFQPIFLLSGYTMWIRINHSLGSLDSPPTCVLPDSVVKPLPPSSVKAEITINIGLLKISWEKPVFPENNLQFQIRYGLSGKEVQWKMYEVYDAKSKSVSLPVPDLCAVYAVQVRCKRLDGLGYWSNWSNPAYTVVMDIKVPMRGPEFWRIINGDTMKKEKNVTLLWKPLMKNDSLCSVQRYVINHHTSCNGTWSEDVGNHTKFTFLWTEQAHTVTVLAINSIGASVANFNLTFSWPMSKVNIVQSLSAYPLNSSCVIVSWILSPSDYKLMYFIIEWKNLNEDGEIKWLRISSSVKKYYIHDHFIPIEKYQFSLYPIFMEGVGKPKIINSFTQDDIEKHQSDAGLYVIVPVIISSSILLLGTLLISHQRMKKLFWEDVPNPKNCSWAQGLNFQKPETFEHLFIKHTASVTCGPLLLEPETISEDISVDTSWKNKDEMMPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEVTYEDESQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPLKDSFSNSSWEIEAQAFFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYLGVTSIKKRESGVLLTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFASYMPQFQTCSTQTHKIMENKMCDLTV

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 19 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
23	N-linked (GlcNAc...) asparagine	9786864		UniProt GlyGen
41	N-linked (GlcNAc...) asparagine	9786864		UniProt GlyGen
56	N-linked (GlcNAc...) asparagine	9786864	G80920RR	UniProt GlyGen
73	N-linked (GlcNAc...) asparagine	9786864	G26436YP G88619MM G10019LZ G38663NM G37881RL G22310AV G48414YA G84452RH	GlycoProtDB UniProt GlyGen GlyConnect
81	N-linked (GlcNAc...) asparagine	9786864	G26436YP	GlycoProtDB UniProt GlyGen
98	N-linked (GlcNAc...) asparagine	9786864	G37881RL G11629QQ G84452RH G80920RR	UniProt GlyGen GlyConnect
187	N-linked (GlcNAc...) asparagine	9786864	G80920RR	UniProt GlyGen
206	N-linked (GlcNAc...) asparagine	9786864	G57888GL G11629QQ G56784JY G22310AV G75983OB G48414YA G84452RH G80920RR	UniProt GlyGen GlyConnect
276	N-linked (GlcNAc...) asparagine	16335952 19159218 9786864	G11629QQ G52527GH G80920RR	GlycoProtDB UniProt GlyGen GlyConnect
347	N-linked (GlcNAc...) asparagine	9786864	G33791AF G80920RR G98129XB	UniProt GlyGen GlyConnect