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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
Summary
- UniProt ID
- P48426
- Gene Symbol
-
- PIP4K2A
- PI5P4KA
- PIP5K2
- PIP5K2A
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P48426
- PubChem
- P48426
- SwissLipids
- The Human Metabolome Database
- HMDBP01202
- The O-GlcNAc Database
- P48426
- RaftProt
- P48426
Annotation
- Keyword
-
- 3D-structure
- ATP-binding
- Acetylation
- Alternative splicing
- Cell membrane
- Cell projection
- Cytoplasm
- Direct protein sequencing
- Kinase
- Lipid metabolism
- Lysosome
- Nucleus
- Phosphoprotein
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| plasma membrane |
| cytosol |
| photoreceptor outer segment |
| photoreceptor inner segment |
| nucleoplasm |
| lysosome |
| autophagosome |
Sequence
MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| PI5P Regulates TP53 Acetylation | Homo sapiens |
| PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling | Homo sapiens |
| Synthesis of PIPs at the plasma membrane | Homo sapiens |
| Synthesis of PIPs in the nucleus | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050908 | myelodysplastic syndrome | |
| DOID:0080144 | childhood acute lymphocytic leukemia | |
| DOID:0080147 | lymphoblastic lymphoma | |
| DOID:0080220 | obsolete major affective disorder 1 | |
| DOID:0080221 | obsolete major affective disorder 2 | |
| DOID:1240 | leukemia | |
| DOID:14250 | Down syndrome | |
| DOID:150 | disease of mental health | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer |
