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MIRAGE
PI5P Regulates TP53 Acetylation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TMEM55BTMEM55BPI(4,5)P2PiPI5PH2OADPATPp32ING2:PI5Pp-S15,S20-TP53 TetramerING2:EP300:p-S15,S20-TP53 Tetramerp300Ac-CoAING2:EP300:Ac-K382,p-S15,S20-TP53 TetramerCoAPIP4K2B dimersp-S326-PIP4K2B dimersPIN1p-S326-PIP4K2B dimers:PIN1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P04637 Cellular tumor antigen p53
  • P53
  • TP53
 view
P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
  • PI5P4KA
  • PIP4K2A
  • PIP5K2
  • PIP5K2A
 view
P52564 Dual specificity mitogen-activated protein kinase kinase 6
  • MAP2K6
  • MEK6
  • MKK6
  • PRKMK6
  • SKK3
 view
P78356 Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
  • PIP4K2B
  • PIP5K2B
 view
Q09472 Histone acetyltransferase p300
  • EP300
  • P300
 view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025