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MIRAGE
Cell surface receptor daf-4
Summary
- UniProt ID
- P50488
- Gene Symbol
-
- C05D2.1
- daf-4
- Gene ID
- 175781
- Organism
- Caenorhabditis elegans
External Links
- GlycoProtDB
- GPDB0000528
- PubChem
- P50488
- Re-Glyco
- P50488
Annotation
- Keyword
-
- ATP-binding
- Cell membrane
- Developmental protein
- Glycoprotein
- Receptor
- Reference proteome
- Serine/threonine-protein kinase
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| receptor complex |
| plasma membrane |
Sequence
MNQKGTVRLKALVLICLPLFLIATPVPVAVTEDDRQDRIESEAAEKEWANTLVSKVAQSNGTGTIKVSAPAKPTLRRMDNEEDEVISIECVYYDEMECEKSGDCEITKKTCYSEAHLKAVGCLAVFGLPTQEINSTEPYLKVDKPQYKSLGCMPYQHADSMNCENESSCRQGRSFRGGIGMCCCSTNNCNMPDLIEMVNPSLKKDSDNSALLWASTPSNMDLESLDKFPFYWIIIIALSVILCIALLILAYVGWKFQQNKKEEIKKQQKIKFDMEKTDALEAGNVPLVEPEEEMIEMVETPKELPITDFQLISKGRFGKVFKAQYTPDSGEKRLVAVKKLNEFQKASFLAEKRIFDELNEYPKWYKSIVEFVCAEKIGDEYWIVTEFHERLSLYELLKNNVISITSANRIIMSMIDGLQFLHDDRPYFFGHPKKPIIHRDIKSKNILVKSDMTTCIADFGLARIYSYDIEQSDLLGQVGTKRYMSPEMLEGATEFTPTAFKAMDVYSMGLVMWEVISRTKLHQTDEPPNYQMPFQVIGFDPTIGLMRNYVVSKKERPQWRDEIIKHEYMSLLKKVTEEMWDPEACARITAGCAFARVWNHIMSSPDSSEGYHSGSSMKNRGVDDVEQSEKPEGIEEMQHYHASSPSKRQHPSPNPFFDSCPPPPPIPVILENGGILQPDNAEPEPEELPDLPIVEKIYDIATNMLFSREELDLMNAQRQVEYEAGADTRASTPTPSGTFGTFTT
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 60 | N-linked (GlcNAc...) asparagine |
|
||
| 134 | N-linked (GlcNAc...) asparagine |
|
||
| 165 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Downregulation of TGF-beta receptor signaling | Caenorhabditis elegans |
| Signaling by BMP | Caenorhabditis elegans |
| TGF-beta receptor signaling activates SMADs | Caenorhabditis elegans |
| TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | Caenorhabditis elegans |
| TGFBR3 regulates TGF-beta signaling | Caenorhabditis elegans |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:14323 | Marfan syndrome |
