TGF-beta receptor signaling activates SMADs

Summary
Species
Caenorhabditis elegans
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Pre-TGFB1 complexTGF-beta-1:LAP1TGFB1:LAP1nid-1LTBP1,LTBP3:TGFB:LAPTGFB:LAPLAP1 binding-integrinsLTBP1:TGFB1:LAP1:LAP1-binding integrinsLTBP1:TGFB1:LAP1TGFB3:LAP3TGF-beta-3:LAP3:LAP3-binding integrinsLAP3-binding integrinsDimeric TGFB1Dimeric TGFB1:TGFBR2 homodimerTGFBR2TGFBR1:FKBP1ATGFB1:TGFBR2:TGFBR1Homologues of FKBP1AADPTGFB1:TGFBR2:p-TGFBR1ATPaka-1TGFB1:p-TGFBR:ZFYVE9:SMAD2/3daf-8TGFB1:p-TGFBR:ZFYVE9:p-2S-SMAD2,3TGFB1:p-TGFBR:ZFYVE9Q21733SMAD4p-2S-SMAD2,3:SMAD4TGFBR2:CBLCBL
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025