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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Palmitoyl-protein thioesterase 1
Summary
- UniProt ID
- P50897
- Gene Symbol
-
- PPT1
- CLN1
- PPT
- Organism
- Homo sapiens (human)
External Links
- GlycoProtDB
- GPDB0011719
- GlyConnect
- GlyGen
- P50897
- PubChem
- P50897
- The Human Metabolome Database
- HMDBP01050
- The O-GlcNAc Database
- P50897
- O-GlcNAcAtlas
- P50897
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Disease variant
- Disulfide bond
- Glycoprotein
- Hydrolase
- Lysosome
- Neuronal ceroid lipofuscinosis
- Reference proteome
- Secreted
- Signal
- Vision
- Gene Ontology (GO)
| GO Term |
|---|
| neurotransmitter secretion |
| nervous system development |
| brain development |
| visual perception |
| protein transport |
| lipid catabolic process |
| protein catabolic process |
| neuron development |
| response to stimulus |
| sphingolipid catabolic process |
| GO Term |
|---|
| extracellular region |
| nucleus |
| lysosome |
| Golgi apparatus |
| membrane |
| axon |
| intracellular membrane-bounded organelle |
| dendrite |
| neuronal cell body |
| extracellular exosome |
| GO Term |
|---|
| palmitoyl-(protein) hydrolase activity |
| lysophosphatidic acid binding |
| sulfatide binding |
| long-chain acyl-CoA hydrolase activity |
Sequence
MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEKKIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHIIPFLG
Glycosylation Sites
G87123QX
G45395BF
G85554PZ
G58087IP
G83646BJ
G15664MX
G66621EA
G27058EU
G45495MK
G84452RH
G83460ZZ
G41071NU
G49018RC
G42962KI
G44215PV
G20210JR
G23294PN
G70101JE
G80920RR
G73968GN
G90659AW
G77547TA
G64409MC
G62765YT
G64527OM
G62894KT
G11870QZ
G47644PP
G05049YU
G72735IY
G85269DF
G72291OX
G95865ZB
G05724UK
G31852PQ
G90575OW
G23719VF
G33609NS
G11314AS
G29880MM
G39188ZX
G41247ZX
G25637MV
G50282JC
G02815KT
G06110VR
G00406II
G84349RE
G92050GC
G74724QE
G92275SC
G14669DU
G28681TP
G54010QB
G49108TO
G33416PL
G72667IM
G39619TI
G51640FO
G59626AS
G01650EU
G02886BB
G45504EY
G37399XV
G10486CT
G28541PG
G20528HD
G40834TG
G22310AV
G04672QB
G08918WF
G72797UR
G87661QW
G51653BI
G85582CB
G60033FS
G14994KB
G46503DX
G42124LM
G47950XN
G95177YH
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Fatty acyl-CoA biosynthesis | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110730 | neuronal ceroid lipofuscinosis 6B | |
| DOID:0110731 | neuronal ceroid lipofuscinosis 3 | |
| DOID:0110732 | neuronal ceroid lipofuscinosis 11 | |
| DOID:0110733 | neuronal ceroid lipofuscinosis 9 | |
| DOID:10283 | prostate cancer | |
| DOID:10286 | prostate carcinoma | |
| DOID:1059 | intellectual disability | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10871 | age related macular degeneration | |
| DOID:10914 | amnestic disorder |
