GlyCosmos Portal

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Lumican

Summary

UniProt ID

P51884

Gene Symbol

LUM
LDC
SLRR2D

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011724

GlyConnect

1470

GlyGen

P51884

PubChem

P51884

The O-GlcNAc Database

P51884

O-GlcNAcAtlas

P51884

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Extracellular matrix
Leucine-rich repeat
Phosphoprotein
Proteoglycan
Pyrrolidone carboxylic acid
Reference proteome
Repeat
Signal
Sulfation

Gene Ontology (GO)

Displaying **all 4** entries
GO Term
positive regulation of transcription by RNA polymerase II
positive regulation of transforming growth factor beta1 production
visual perception
collagen fibril organization

Displaying **all 8** entries
GO Term
extracellular region
fibrillar collagen trimer
extracellular space
extracellular matrix
collagen-containing extracellular matrix
extracellular exosome
Golgi lumen
lysosomal lumen

Displaying **all 3** entries
GO Term
collagen binding
extracellular matrix structural constituent conferring compression resistance
extracellular matrix structural constituent

Annotation information from UniProt.

Sequence

MSLSAFTLFLALIGGTSGQYYDYDFPLSIYGQSSPNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKLGSFEGLVNLTFIHLQHNRLKEDAVSAAFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVNENLENYYLEVNQLEKFDIKSFCKILGPLSYSKIKHLRLDGNRISETSLPPDMYECLRVANEVTLN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 8** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
88	N-linked (GlcNAc...) (keratan sulfate) asparagine	14760718 16335952 19159218	G41271HD G85966UN G52848YE G75006KF G73027HY G74381CZ G64751KD G01521EA G13191RB G63040RU G53075ES G12745LE G76868JS G31309XD G09831WQ G23165GD G71051TA G94665LC G89827JR G67164EE G11101UV G30221QT G39595FH G81637OR G07810QS G67506FN G71463BG G65414LI G50427EO G50856PC G99679NM G82443XX G95046LV G32788FZ G63136LV G01160VV G16136DL G60967DT G39471UU G05962QB G64394MX G30740WO G45526EA G12341GU G70232NH G46450MZ G55132BD G37818NZ G57888GL G69521XL G14547CB G81124ET G70888PK G03644CB G31544HA G47518TP G49589RB G12261QD G35541EV G34617SM G93718GY G13131HA G49755GI G75568BH G20312EM G80075MS G11629QQ G57776ZS G16125XL G29545VG G44753VC G31596VW G68490OW G99668VU G77669RF G60834IK G86795LJ G86880BF G27947YN G52527GH G90382BL G91473PK G30970QQ G30248BL G80479JV G90093AU G85282JO G20528HD G24954UD G78502KD G63980BQ G04854VP G87123QX G79666IR G81263BG G65019XG G92135MA G98611JV G43734MM G34989PA G81198YO G40834TG G43669FQ G22310AV G45395BF G88374WZ G07246CJ G20706XG G10819WX G40926MX G14972EH G02030ZB G43223CG G58954YZ G37412TK G31986NC G40574BA G78787DI G00273SJ G08918WF G00912UN G27915IV G70441OD G87661QW G83646BJ G72667IM G76295SF G46691LC G27126ED G04657PL G27058EU G84452RH G24528MX G51653BI G85582CB G83460ZZ G41071NU G91636VS G07755XJ G86182NS G70619PT G59626AS G84862VB G08290VR G80920RR G03382KH G42124LM G23863VK G90659AW G62765YT G64527OM G47950XN G47644PP G10486CT G05049YU G18647XP G05724UK G96993FE G11314AS G36379GD G92275SC G72197KC G84225JN G89045VA	GlycoProtDB UniProt GlyGen GlyConnect
127	N-linked (GlcNAc...) (keratan sulfate) asparagine		G94310CV G75006KF G26377UA G64751KD G01521EA G13191RB G08609CW G12745LE G76868JS G31309XD G09831WQ G71051TA G94665LC G11115RO G15127JD G67164EE G11101UV G30221QT G81637OR G07810QS G71463BG G65414LI G70894RY G50427EO G50856PC G62461SM G82443XX G95046LV G32788FZ G63136LV G01160VV G60967DT G80669SJ G39471UU G05962QB G32926LW G64394MX G78649WQ G45526EA G12341GU G76417NN G70232NH G46450MZ G19385TO G72951AH G55132BD G37818NZ G57888GL G69521XL G70888PK G03644CB G31544HA G47518TP G35541EV G34617SM G73686WG G93718GY G37881RL G49755GI G75568BH G80075MS G11629QQ G57776ZS G85144OK G16125XL G29545VG G30769VJ G41882MT G44753VC G31596VW G68490OW G75418YA G99668VU G77669RF G60834IK G86795LJ G86880BF G27947YN G52527GH G90382BL G91473PK G30970QQ G49739MP G80479JV G90093AU G02315DX G85282JO G40206WX G20528HD G24954UD G63980BQ G83951ZY G04854VP G94470IW G87123QX G96577RX G79666IR G81263BG G86752LQ G65019XG G84492TS G92135MA G26403SG G98611JV G43734MM G75607BQ G34989PA G81198YO G40834TG G02528FI G43669FQ G08146BT G22310AV G45395BF G88374WZ G59324HL G07246CJ G70375MX G04672QB G85554PZ G02628JF G20706XG G10819WX G40926MX G59536GA G56307ZW G14972EH G22625SJ G69107AL G02030ZB G43223CG G58954YZ G95977AE G37412TK G31986NC G10846ZT G60177UT G40574BA G82830MN G78787DI G00273SJ G83229XP G08918WF G75983OB G00912UN G48414YA G49906RN G27915IV G11911BT G87389XI G23505EP G92551JA G61256FT G44211QA G70441OD G72797UR G70822IO G87661QW G83646BJ G17208MA G63381RX G65807AE G72667IM G76295SF G15664MX G66621EA G46691LC G80223IX G25418HZ G27126ED G66766XF G04657PL G25451PN G87051GH G08293MJ G27058EU G45495MK G84452RH G24528MX G46524LG G51653BI G85582CB G43769HG G96091TT G51640FO G70223PD G10488MI G60033FS G41071NU G85740DB G91636VS G07755XJ G70418MS G24835MQ G86182NS G35253PZ G72747WU G44215PV G70619PT G06356OH G59626AS G08290VR G14994KB G92406TI G41840AI G01650EU G23294PN G25079LO G70101JE G80920RR G47702MW G63041LO G01485JJ G73968GN G65184UU G03382KH G42124LM G02886BB G23863VK G83555HU G90659AW G74430RZ G77547TA G45504EY G59924QI G29299MO G37399XV G82463GQ G62765YT G11870QZ G47644PP G88891KO G72790NZ G95177YH G10486CT G05049YU G28541PG G18647XP G72291OX G95865ZB G31852PQ G23719VF G39446WN G11314AS G57776ZU G02815KT G06110VR G54010QB G84225JN G89045VA G98129XB	GlycoProtDB UniProt GlyGen GlyConnect
160	N-linked (GlcNAc...) (keratan sulfate) asparagine	14760718 16335952 19159218	G41271HD G85966UN G75006KF G73027HY G66537LK G64751KD G01521EA G13910DJ G13191RB G63040RU G76868JS G31309XD G09831WQ G94665LC G11115RO G89827JR G67164EE G30221QT G81637OR G07810QS G71463BG G50856PC G99679NM G95046LV G32788FZ G56518TU G01160VV G60967DT G05962QB G30740WO G45526EA G12341GU G70232NH G55132BD G37818NZ G69521XL G03644CB G06247RL G35541EV G93718GY G80075MS G11629QQ G57776ZS G16125XL G29545VG G44753VC G68490OW G77669RF G86880BF G27947YN G52527GH G30970QQ G80479JV G85282JO G20528HD G63980BQ G04854VP G94470IW G87123QX G79666IR G81263BG G92135MA G98611JV G43734MM G34989PA G40834TG G43669FQ G45395BF G59324HL G07246CJ G85554PZ G20706XG G10819WX G40926MX G59536GA G43223CG G58954YZ G37412TK G00273SJ G08918WF G00912UN G48414YA G49906RN G27915IV G61256FT G70441OD G87661QW G83646BJ G76295SF G04657PL G27058EU G84452RH G43769HG G60033FS G41071NU G86182NS G70619PT G59626AS G70101JE G80920RR G65184UU G03382KH G42124LM G90659AW G62765YT G64527OM G10486CT G05724UK G31852PQ G11314AS G41247ZX G36379GD G06110VR G98129XB	GlycoProtDB UniProt GlyGen GlyConnect
201			G49108TO	GlyGen The O-GlcNAc Database
209			G49108TO	GlyGen The O-GlcNAc Database
252	N-linked (GlcNAc...) (keratan sulfate) asparagine		G75006KF G57581QG G74381CZ G64751KD G01521EA G09700PF G63040RU G69834CE G12745LE G76868JS G31309XD G09831WQ G23165GD G71051TA G94665LC G89827JR G15127JD G67164EE G30221QT G94831VI G39595FH G81637OR G07810QS G71463BG G50856PC G95046LV G32788FZ G56518TU G60967DT G39471UU G05962QB G64394MX G30740WO G45526EA G12341GU G15169WU G70232NH G55132BD G37818NZ G03644CB G35541EV G93718GY G85677PP G75568BH G80075MS G11629QQ G57776ZS G16125XL G29545VG G41882MT G44753VC G68490OW G99668VU G77669RF G60834IK G86880BF G27947YN G30970QQ G80479JV G85282JO G20528HD G63980BQ G04854VP G94470IW G87123QX G79666IR G98611JV G40834TG G02528FI G43669FQ G45395BF G59324HL G07246CJ G85554PZ G20706XG G10819WX G40926MX G59536GA G14972EH G43223CG G49642SA G10846ZT G40574BA G78787DI G00273SJ G08918WF G00912UN G48414YA G27915IV G92551JA G70441OD G87661QW G83646BJ G17208MA G72667IM G76295SF G04657PL G27058EU G84452RH G24528MX G43769HG G96091TT G60033FS G41071NU G07755XJ G86182NS G70619PT G59626AS G80920RR G01485JJ G73968GN G65184UU G03382KH G42124LM G90659AW G83633GK G88891KO G72790NZ G95177YH G10486CT G31852PQ G41247ZX G02815KT G89045VA G98129XB	GlycoProtDB UniProt GlyGen GlyConnect
320			G43417UB	GlyGen
				GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 7** entries
Pathway Name	Organism
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	Homo sapiens
Defective CHST6 causes MCDC1	Homo sapiens
Defective ST3GAL3 causes MCT12 and EIEE15	Homo sapiens
ECM proteoglycans	Homo sapiens
Integrin cell surface interactions	Homo sapiens
Keratan sulfate biosynthesis	Homo sapiens
Keratan sulfate degradation	Homo sapiens

Human Protein Atlas

ENSG00000139329

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements