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Dipeptidyl peptidase 1

Summary

UniProt ID

P53634

Gene Symbol

CTSC
CPPI

Organism

Homo sapiens (human)

External Links

GlycoProtDB

GPDB0011727

GlyConnect

1175

GlyGen

P53634

PubChem

P53634

The Human Metabolome Database

HMDBP08180

The O-GlcNAc Database

P53634

RaftProt

P53634

Annotation

Keyword

3D-structure
Alternative splicing
Chloride
Direct protein sequencing
Disease variant
Disulfide bond
Glycoprotein
Lysosome
Palmoplantar keratoderma
Reference proteome
Signal
Thiol protease
Zymogen

Gene Ontology (GO)

Displaying **all 9** entries
GO Term
T cell mediated cytotoxicity
proteolysis
immune response
response to organic substance
proteolysis involved in protein catabolic process
positive regulation of proteolysis involved in protein catabolic process
negative regulation of myelination
positive regulation of microglial cell activation
positive regulation of apoptotic signaling pathway

Displaying entries **1 - 10** of 13 in total

1

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GO Term
extracellular region
extracellular space
lysosome
membrane
intracellular membrane-bounded organelle
collagen-containing extracellular matrix
extracellular exosome
nucleoplasm
centrosome
endoplasmic reticulum lumen

Displaying **all 10** entries
GO Term
cysteine-type peptidase activity
peptidase activator activity involved in apoptotic process
protein-folding chaperone binding
chloride ion binding
identical protein binding
serine-type endopeptidase activity
phosphatase binding
cysteine-type endopeptidase activity
dipeptidyl-peptidase activity
protein self-association

Annotation information from UniProt.

Sequence

MGAGPSLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVVYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVTTYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNIAHLKNSQEKYSNRLYKYDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHTGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPIPKL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 6** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
29	N-linked (GlcNAc...) asparagine	11726493 19167329	G84452RH G14260UH G64527OM G05724UK G29880MM G39188ZX G06110VR G39066MP	UniProt GlyGen GlyConnect
53	N-linked (GlcNAc...) asparagine	19159218 19167329	G57888GL G37881RL G11629QQ G77669RF G63980BQ G45395BF G14972EH G43223CG G26330YA G00912UN G11911BT G99966GV G87661QW G66760KM G36442WJ G15664MX G66621EA G27126ED G66766XF G04657PL G27058EU G45495MK G84452RH G46524LG G83460ZZ G23984SE G29184RN G10773YW G96091TT G51640FO G70223PD G41071NU G07755XJ G49018RC G72747WU G08290VR G92406TI G20210JR G01650EU G23294PN G70101JE G80920RR G42124LM G02886BB G65092SV G90659AW G64409MC G59924QI G29299MO G37399XV G83633GK G62765YT G64527OM G62894KT G11870QZ G47644PP G95177YH G05049YU G28541PG G72735IY G18647XP G85269DF G72291OX G95865ZB G05724UK G31852PQ G90575OW G23719VF G39446WN G11314AS G39188ZX G41247ZX G25637MV G50282JC G36379GD G02815KT G06110VR G92050GC G74724QE G92275SC G28681TP G84225JN	GlycoProtDB UniProt GlyGen GlyConnect
119	N-linked (GlcNAc...) asparagine	19167329	G13131HA G68490OW G85282JO G24954UD G63980BQ G04854VP G08918WF G00912UN G46691LC G27126ED G51640FO G07755XJ G49018RC G72747WU G46503DX G25079LO G80920RR G01485JJ G50757KG G73968GN G65184UU G42124LM G02886BB G23863VK G90659AW G77547TA G62765YT G88891KO G72790NZ G95177YH G10486CT G05049YU G46687AB G90734RJ G28541PG G72735IY G18647XP G55383ZG G85269DF G92597CK G72291OX G95865ZB G05724UK G31852PQ G96993FE G31936TA G72787SB G23719VF G33609NS G39446WN G11314AS G39188ZX G41247ZX G25637MV G35029YA G57776ZU G02815KT G06110VR G00406II G57317CE G92050GC G92275SC G14669DU G28681TP G54010QB G89045VA	UniProt GlyGen GlyConnect
276	N-linked (GlcNAc...) asparagine	19167329	G11629QQ G81263BG G47012YE G22310AV G66163OV G22625SJ G02030ZB G95977AE G83229XP G48414YA G99966GV G72797UR G70822IO G25451PN G84452RH G70418MS G46902YN G47448YK G23863VK G14260UH G62894KT G11870QZ G46687AB G55383ZG G05724UK G33609NS G39188ZX G94854LT G06110VR G74724QE G14669DU	UniProt GlyGen GlyConnect
277				GlyGen
			G49108TO	GlyGen The O-GlcNAc Database GlyConnect

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
COPII-mediated vesicle transport	Homo sapiens
Cargo concentration in the ER	Homo sapiens
MHC class II antigen presentation	Homo sapiens
Neutrophil degranulation	Homo sapiens

Human Protein Atlas

ENSG00000109861

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

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Summary

External Links

Annotation

International Collaboration

Acknowledgements