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LIM domain kinase 1
Summary
- UniProt ID
- P53668
- Gene Symbol
-
- Limk
- Limk1
- Gene ID
- 16885
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Cell projection
- Cytoskeleton
- LIM domain
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Serine/threonine-protein kinase
- Ubl conjugation
- Gene Ontology (GO)
| GO Term |
|---|
| neuron projection |
| postsynapse |
| cytosol |
| focal adhesion |
| lamellipodium |
| nuclear speck |
| glutamatergic synapse |
| male germ cell nucleus |
| nucleus |
| cytoplasm |
| GO Term |
|---|
| positive regulation of axon extension |
| axon extension |
| positive regulation of stress fiber assembly |
| protein phosphorylation |
| stress fiber assembly |
Sequence
MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCECSVSLSHQYYEKDGQLFCKKDYWARYGESCHGCSEHITKGLVMVAGELKYHPECFICLACGNFIGDGDTYTLVEHSKLYCGQCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASAHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDSLGHGPVSDPSPLSSPVHTPSGQAASSARQKPVLRSCSIDTSPGTSSLASPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSEDLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLSGHLPLGPQLEQLERGFWETYRRGESSLPAHPEVPD
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 20 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| RHO GTPases activate PAKs | Mus musculus |
| Regulation of actin dynamics for phagocytic cup formation | Mus musculus |
| Sema3A PAK dependent Axon repulsion | Mus musculus |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1928 | Williams-Beuren syndrome |
