RHO GTPases activate PAKs

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Active RAC1/CDC42PAK1PAK1 dimerRAC1:GTP,CDC42:GTP:PAK1LIMK1P53668ADPATPCDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3p-S,T-PAK1,2,3PAK2 dimerCDC42:GTP,RAC1:GTP:PAK2PAK2CDC42:GTP,RAC1:GTP:PAK3PAK3 dimerPak3p-T19-MRLC-Smooth muscle/non-muscle myosin IISmooth muscle/non-muscle myosin IIMyosin phosphatasep-T696-PPP1R12A-Myosin phosphataseCalmodulin:CalciumMYLK:Ca2+:CALM1Q6PDN3Q6PDN3Nf2PAK1:NF2O88643p-S144,T423-PAK1:FLNAFLNAp-S2152-FLNA
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
a simple tooltip

About Release Notes Help Feedback

Click here to visit the beta site.


International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International


GlyCosmos Portal v4.2.1

Last updated: April 7, 2025