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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
DNA polymerase epsilon subunit 2
Summary
- UniProt ID
- P56282
- Gene Symbol
-
- POLE2
- DPE2
- Organism
- Homo sapiens (human)
External Links
- GlyGen
- P56282
- PubChem
- P56282
- The Human Metabolome Database
- HMDBP00970
- The O-GlcNAc Database
- P56282
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- DNA replication
- DNA-binding
- Nucleus
- Reference proteome
- Gene Ontology (GO)
| GO Term |
|---|
| DNA repair |
| DNA replication |
| DNA-templated DNA replication |
| error-prone translesion synthesis |
| GO Term |
|---|
| intracellular membrane-bounded organelle |
| nucleoplasm |
| epsilon DNA polymerase complex |
| nuclear body |
| GO Term |
|---|
| DNA binding |
| DNA-directed DNA polymerase activity |
Sequence
MAPERLRSRALSAFKLRGLLLRGEAIKYLTEALQSISELELEDKLEKIINAVEKQPLSSNMIERSVVEAAVQECSQSVDETIEHVFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLFGTPRDKAEMFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTTKIGDAIVLGMITQLKEGKFFLEDPTGTVQLDLSKAQFHSGLYTEACFVLAEGWFEDQVFHVNAFGFPPTEPSSTTRAYYGNINFFGGPSNTSVKTSAKLKQLEEENKDAMFVFLSDVWLDQVEVLEKLRIMFAGYSPAPPTCFILCGNFSSAPYGKNQVQALKDSLKTLADIICEYPDIHQSSRFVFVPGPEDPGFGSILPRPPLAESITNEFRQRVPFSVFTTNPCRIQYCTQEITVFREDLVNKMCRNCVRFPSSNLAIPNHFVKTILSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVIADKYDPFTTTNTECLCINPGSFPRSGFSFKVFYPSNKTVEDSKLQGF
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 174 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Activation of the pre-replicative complex | Homo sapiens |
| DNA replication initiation | Homo sapiens |
| Dual Incision in GG-NER | Homo sapiens |
| Dual incision in TC-NER | Homo sapiens |
| Gap-filling DNA repair synthesis and ligation in GG-NER | Homo sapiens |
| Gap-filling DNA repair synthesis and ligation in TC-NER | Homo sapiens |
| HDR through Homologous Recombination (HRR) | Homo sapiens |
| PCNA-Dependent Long Patch Base Excision Repair | Homo sapiens |
| Recognition of DNA damage by PCNA-containing replication complex | Homo sapiens |
| Termination of translesion DNA synthesis | Homo sapiens |
