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Lysine-specific demethylase 2A

Summary

UniProt ID

P59997

Gene Symbol

Kdm2a
Fbl11
Fbxl11
Jhdm1a
Kiaa1004

Organism

Mus musculus (house mouse)

External Links

GlyGen: P59997

Annotation

Keyword

3D-structure
ADP-ribosylation
Allosteric enzyme
Alternative splicing
Biological rhythms
Chromatin regulator
Chromosome
DNA-binding
Dioxygenase
Iron
Isopeptide bond
Leucine-rich repeat
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
Transcription regulation
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Gene Ontology (GO)

Displaying entries **1 - 10** of 14 in total

1

2

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GO Term
regulation of transcription by RNA polymerase II
regulation of circadian rhythm
heart looping
negative regulation of transcription by competitive promoter binding
circadian regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression
neuron differentiation
neuroepithelial cell differentiation
multicellular organism growth

Displaying **all 2** entries
GO Term
chromatin
nucleoplasm

Displaying **all 6** entries
GO Term
histone H3K36 demethylase activity
unmethylated CpG binding
transcription coregulator activity
zinc ion binding
histone demethylase activity
histone H3K36me/H3K36me2 demethylase activity

Annotation information from UniProt.

Sequence

MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLQTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQWPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLISVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLTKDFQKESLSMDMELNELESGNGDEEGVDREARRMNNKRSVLTSPVANGVNLDYDGLGKACRSLPSLKKTLSGDSSSDSTRGSHNGQVWDPQCSPKKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLALTGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSDKAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSSPGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSYLTVTLQRPTKELHGTSIVPKLQAITASSANLRPNPRVLMQHCPARNPQHGDEEGLGGEEEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRKELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSINSLYCLSDEKLIQKIS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites