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Sodium/calcium exchanger 1

Summary

UniProt ID

P70414

Gene Symbol

Slc8a1
Ncx

Organism

Mus musculus (house mouse)

External Links

PubChem: P70414

Annotation

Keyword

Antiport
Calcium transport
Calmodulin-binding
Cell membrane
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Sodium transport
Transmembrane helix

Gene Ontology (GO)

Displaying entries **31 - 38** of 38 in total

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GO Term
sodium ion export across plasma membrane
calcium ion import
cellular response to caffeine
cellular response to cAMP
regulation of cardiac muscle cell membrane potential
cell communication by electrical coupling involved in cardiac conduction
calcium ion import across plasma membrane
calcium ion export

Displaying entries **11 - 19** of 19 in total

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GO Term
postsynapse
basolateral plasma membrane
Z disc
T-tubule
sarcolemma
dendritic shaft
postsynaptic density
intercalated disc
dendritic spine

Displaying **all 8** entries
GO Term
calcium ion binding
calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential
monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential
calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration
ankyrin binding
transmembrane transporter binding
calcium:sodium antiporter activity
calmodulin binding

Annotation information from UniProt.

Sequence

MLRLSLPPNVSMGFRLVALVALLFSHVDHITADTEAETGGNETTECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGDLSTTVFVDFRTEDGTANAASDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILESNHASSIACLGSPSTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGEPEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKALLLNELGGFTLTGKEMYGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIQESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
41	N-linked (GlcNAc...) asparagine			UniProt
157	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Ion homeostasis	Mus musculus
Reduction of cytosolic Ca++ levels	Mus musculus
Sodium/Calcium exchangers	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements