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Sodium/calcium exchanger 1

Summary

UniProt ID

P70414

Gene Symbol

Slc8a1
Ncx

Organism

Mus musculus (house mouse)

External Links

PubChem: P70414

Annotation

Keyword

Antiport
Calcium transport
Calmodulin-binding
Cell membrane
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Signal
Sodium transport
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 38 in total

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GO Term
embryonic placenta development
regulation of heart rate
regulation of sodium ion transport
heart morphogenesis
sodium ion transport
calcium ion transport
intracellular calcium ion homeostasis
post-embryonic development
regulation of gene expression
embryonic heart tube development

Displaying entries **11 - 19** of 19 in total

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2
GO Term
postsynapse
basolateral plasma membrane
Z disc
T-tubule
sarcolemma
dendritic shaft
postsynaptic density
intercalated disc
dendritic spine

Displaying **all 8** entries
GO Term
calcium ion binding
ankyrin binding
transmembrane transporter binding
calcium:sodium antiporter activity
calmodulin binding
calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential
monoatomic ion antiporter activity involved in regulation of postsynaptic membrane potential
calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration

Annotation information from UniProt.

Sequence

MLRLSLPPNVSMGFRLVALVALLFSHVDHITADTEAETGGNETTECTGSYYCKKGVILPIWEPQDPSFGDKIARATVYFVAMVYMFLGVSIIADRFMSSIEVITSQEKEITIKKPNGETTKTTVRIWNETVSNLTLMALGSSAPEILLSVIEVCGHNFTAGDLGPSTIVGSAAFNMFIIIALCVYVVPDGETRKIKHLRVFFVTAAWSIFAYTWLYIILSVSSPGVVEVWEGLLTFFFFPICVVFAWVADRRLLFYKYVYKRYRAGKQRGMIIEHEGDRPASKTEIEMDGKVVNSHVDNFLDGALVLEVDERDQDDEEARREMARILKELKQKHPEKEIEQLIELANYQVLSQQQKSRAFYRIQATRLMTGAGNILKRHAADQARKAVSMHEVNMEMAENDPVSKIFFEQGTYQCLENCGTVALTIMRRGGDLSTTVFVDFRTEDGTANAASDYEFTEGTVIFKPGETQKEIRVGIIDDDIFEEDENFLVHLSNVRVSSDVSEDGILESNHASSIACLGSPSTATITIFDDDHAGIFTFEEPVTHVSESIGIMEVKVLRTSGARGNVIIPYKTIEGTARGGGEDFEDTCGEPEFQNDEIVKTISVKVIDDEEYEKNKTFFIEIGEPRLVEMSEKKALLLNELGGFTLTGKEMYGQPIFRKVHARDHPIPSTVITISEEYDDKQPLTSKEEEERRIAEMGRPILGEHTKLEVIIQESYEFKSTVDKLIKKTNLALVVGTNSWREQFIEAITVSAGEDDDDDECGEEKLPSCFDYVMHFLTVFWKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALGTSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVGVLLYRRRPEIGGELGGPRTAKLLTSSLFVLLWLLYIFFSSLEAYCHIKGF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
41	N-linked (GlcNAc...) asparagine			UniProt
157	N-linked (GlcNAc...) asparagine			UniProt

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Ion homeostasis	Mus musculus
Reduction of cytosolic Ca++ levels	Mus musculus
Sodium/Calcium exchangers	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

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Summary

External Links

Annotation

International Collaboration

Acknowledgements