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Tyrosine-protein phosphatase non-receptor type substrate 1

Summary

UniProt ID

P97710

Gene Symbol

Sirpa
Bit
Mfr
Ptpns1
Shps1
Sirp

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: P97710
PubChem: P97710

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
SH3-binding
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 36 in total

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GO Term
actin filament organization
hematopoietic progenitor cell differentiation
cytoskeleton organization
regulation of gene expression
cell migration
regulation of type II interferon production
cell motility
negative regulation of inflammatory response
negative regulation of phagocytosis
positive regulation of phagocytosis

Displaying **all 2** entries
GO Term
cell surface
plasma membrane

Displaying **all 8** entries
GO Term
protein binding involved in heterotypic cell-cell adhesion
protein phosphorylated amino acid binding
SH3 domain binding
protein phosphatase binding
GTPase regulator activity
cell-cell adhesion mediator activity
protein tyrosine kinase binding
protein antigen binding

Annotation information from UniProt.

Sequence

MEPAGPAPGRLGPLLFCLLLSASCFCAGASGKELKVTQADKSVSVAAGDSATLNCTVSSLTPVGPIKWFKGEGQNRSPIYSFIGGEHFPRITNVSDATKRNNMDFSICISNVTPEDAGTYYCVKFQKGIVEPDTEIKSGGGTTLYVLAKPSSPEVSGPDSRGSPGQTVNFTCKSYGFSPRNITLKWLKDGKELSHLETTISSKSNVSYNISSTVSVKLSPEDIHSRVICEVAHVTLEGRPLNGTANFSNIIRVSPTLKITQQPLTPASQVNLTCQVQKFYPKALQLNWLENGNLSRTDKPEHFTDNRDGTYNYTSLFLVNSSAHREDVVFTCQVEHDSQPAITENHTVRAFAHSSSGGSMETIPDNNAYYNWNVFIGVGVACALLVVLLMAALYLLRIKQKKAKGSTSSTRLHEPEKNAREITQIQDTNDINDITYADLNLPKEKKPAPRVPEPNNHTEYASIETGKLPRPEDTLTYADLDMVHLNRAQPTPKPEPSFSEYASVQVQRK

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying entries **1 - 10** of 13 in total

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Position	Description	PubMed ID	GlyTouCan ID	Source
54	N-linked (GlcNAc...) asparagine			UniProt GlyGen
93	N-linked (GlcNAc...) asparagine	24090084	G60923RB G80920RR G67324HN G68318VE G83555HU G03574QJ G27622TD G62765YT G88725PI G10486CT G59937CP G31852PQ G72787SB G25987BV G39446WN G41247ZX G02815KT G92050GC	UniProt GlyGen
169	N-linked (GlcNAc...) asparagine	24090084	G09197ZW G80920RR G68318VE G02886BB G83555HU G27622TD G88725PI G10486CT G59937CP G92597CK G49955PK G72787SB G25987BV G39446WN G02815KT	UniProt GlyGen
181	N-linked (GlcNAc...) asparagine			UniProt GlyGen
205	N-linked (GlcNAc...) asparagine			UniProt GlyGen
209	N-linked (GlcNAc...) asparagine			UniProt GlyGen
242	N-linked (GlcNAc...) asparagine			UniProt GlyGen
246	N-linked (GlcNAc...) asparagine			UniProt GlyGen
271	N-linked (GlcNAc...) asparagine			UniProt GlyGen
293	N-linked (GlcNAc...) asparagine			UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 3** entries
Pathway Name	Organism
Cell surface interactions at the vascular wall	Rattus norvegicus
Neutrophil degranulation	Rattus norvegicus
Signal regulatory protein family interactions	Rattus norvegicus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

International Collaboration

Acknowledgements