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Forkhead box protein O4

Summary

UniProt ID

P98177

Gene Symbol

FOXO4
AFX
AFX1
MLLT7

Organism

Homo sapiens (human)

External Links

GlyGen: P98177
PubChem: P98177
The Human Metabolome Database: HMDBP08863

Annotation

Keyword

3D-structure
Acetylation
Activator
Alternative splicing
Cell cycle
Chromosomal rearrangement
Cytoplasm
DNA-binding
Developmental protein
Differentiation
Myogenesis
Nucleus
Pharmaceutical
Phosphoprotein
Proto-oncogene
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 15 in total

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GO Term
regulation of DNA-templated transcription
muscle organ development
positive regulation of transcription by RNA polymerase II
stem cell differentiation
negative regulation of cell population proliferation
negative regulation of angiogenesis
response to nutrient levels
mitotic G2 DNA damage checkpoint signaling
negative regulation of G0 to G1 transition
response to water-immersion restraint stress

Displaying **all 6** entries
GO Term
nucleoplasm
cytosol
chromatin
nucleus
cytoplasm
nuclear speck

Displaying entries **1 - 10** of 13 in total

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GO Term
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity, RNA polymerase II-specific
nucleic acid binding
DNA binding
DNA-binding transcription factor activity
enzyme binding
identical protein binding
sequence-specific DNA binding
DNA-binding transcription factor binding

Annotation information from UniProt.

Sequence

MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPEPAGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSAGEGCFSSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLCPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFEPDP

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
229				GlyGen
263			G02815KT	GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 9** entries
Pathway Name	Organism
AKT phosphorylates targets in the nucleus	Homo sapiens
Cardiogenesis	Homo sapiens
Constitutive Signaling by AKT1 E17K in Cancer	Homo sapiens
FOXO-mediated transcription of cell cycle genes	Homo sapiens
FOXO-mediated transcription of cell death genes	Homo sapiens
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	Homo sapiens
Regulation of FOXO transcriptional activity by acetylation	Homo sapiens
Regulation of localization of FOXO transcription factors	Homo sapiens
Ub-specific processing proteases	Homo sapiens