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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Methyl-CpG-binding protein 2
Summary
- UniProt ID
- Q00566
- Gene Symbol
-
- Mecp2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Acetylation
- Alternative splicing
- DNA-binding
- Direct protein sequencing
- Methylation
- Nucleus
- Phosphoprotein
- Reference proteome
- Repeat
- Repressor
- Transcription regulation
- Gene Ontology (GO)
| GO Term |
|---|
| cytoplasm |
| nucleoplasm |
| cytosol |
| chromatin |
| heterochromatin |
| nucleus |
| protein-containing complex |
| postsynapse |
| centrosome |
| glutamatergic synapse |
| GO Term |
|---|
| histone reader activity |
| nucleic acid binding |
| DNA binding |
| transcription corepressor activity |
| mRNA binding |
| methyl-CpG binding |
| double-stranded methylated DNA binding |
| enzyme binding |
| protein domain specific binding |
| chromatin DNA binding |
Sequence
MVAGMLGLRKEKSEDQDLQGLKEKPLKFKKVKKDKKEDKEGKHEPLQPSAHHSAEPAEAGKAETSESSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTGRPKAAASEGVQVKRVLEKSPGKLLVKMPFQASPGGKGEGGGATTSAQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHAESPKAPMPLLPPPPPPEPQSSEDPISPPEPQDLSSSICKEEKMPRAGSLESDGCPKEPAKTQPMVAAAATTTTTTTTTVAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 49 |
|
|||
| 53 |
|
|||
| 65 |
|
|||
| 134 |
|
|||
| 204 |
|
|||
| 434 |
|
|||
| 443 |
|
|||
| 444 |
|
|||
| 485 |
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Regulation of MECP2 expression and activity | Rattus norvegicus |
