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Methyl-CpG-binding protein 2

Summary

UniProt ID

Q00566

Gene Symbol

Mecp2

Gene ID

29386

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q00566
PubChem: Q00566
The O-GlcNAc Database: Q00566
O-GlcNAcAtlas: Q00566
Re-Glyco: Q00566

Annotation

Keyword

Acetylation
Alternative splicing
DNA-binding
Direct protein sequencing
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
Transcription regulation

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
chromatin
heterochromatin
nucleus
cytoplasm
protein-containing complex
postsynapse
nucleoplasm
cytosol
centrosome
glutamatergic synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 96 in total

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GO Term
chemical synaptic transmission
respiratory gaseous exchange by respiratory system
memory
protein localization
glucocorticoid metabolic process
cell population proliferation
post-embryonic development
regulation of gene expression
positive regulation of gene expression
negative regulation of gene expression

Displaying entries **1 - 10** of 19 in total

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GO Term
chromatin binding
methyl-CpG binding
histone reader activity
double-stranded methylated DNA binding
enzyme binding
protein domain specific binding
chromatin DNA binding
identical protein binding
histone deacetylase binding
molecular adaptor activity

Annotation information from UniProt.

Sequence

MVAGMLGLRKEKSEDQDLQGLKEKPLKFKKVKKDKKEDKEGKHEPLQPSAHHSAEPAEAGKAETSESSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTGRPKAAASEGVQVKRVLEKSPGKLLVKMPFQASPGGKGEGGGATTSAQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHAESPKAPMPLLPPPPPPEPQSSEDPISPPEPQDLSSSICKEEKMPRAGSLESDGCPKEPAKTQPMVAAAATTTTTTTTTVAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	GlyTouCan ID	Source
49	G49108TO	GlyGen The O-GlcNAc Database
53	G49108TO	GlyGen The O-GlcNAc Database
65	G49108TO	GlyGen The O-GlcNAc Database
134	G49108TO	The O-GlcNAc Database
204	G49108TO	The O-GlcNAc Database
434	G49108TO	GlyGen The O-GlcNAc Database
443	G49108TO	GlyGen The O-GlcNAc Database
444	G49108TO	GlyGen The O-GlcNAc Database
485	G49108TO	GlyGen The O-GlcNAc Database