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Methyl-CpG-binding protein 2

Summary

UniProt ID

Q00566

Gene Symbol

Mecp2

Gene ID

29386

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q00566
PubChem: Q00566
The O-GlcNAc Database: Q00566
O-GlcNAcAtlas: Q00566
Re-Glyco: Q00566

Annotation

Keyword

Acetylation
Alternative splicing
DNA-binding
Direct protein sequencing
Methylation
Nucleus
Phosphoprotein
Reference proteome
Repeat
Repressor
Transcription regulation

Gene Ontology (GO)

Displaying **all 10** entries
GO Term
chromatin
heterochromatin
nucleus
cytoplasm
protein-containing complex
postsynapse
nucleoplasm
cytosol
centrosome
glutamatergic synapse

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 96 in total

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GO Term
excitatory postsynaptic potential
negative regulation of locomotion involved in locomotory behavior
negative regulation of respiratory gaseous exchange
gene expression
response to hypoxia
startle response
nervous system process involved in regulation of systemic arterial blood pressure
regulation of respiratory gaseous exchange by nervous system process
chemical synaptic transmission
respiratory gaseous exchange by respiratory system

Displaying entries **11 - 19** of 19 in total

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GO Term
chromatin DNA binding
identical protein binding
histone deacetylase binding
molecular adaptor activity
molecular condensate scaffold activity
promoter-specific chromatin binding
four-way junction DNA binding
siRNA binding
unmethylated CpG binding

Annotation information from UniProt.

Sequence

MVAGMLGLRKEKSEDQDLQGLKEKPLKFKKVKKDKKEDKEGKHEPLQPSAHHSAEPAEAGKAETSESSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTGRPKAAASEGVQVKRVLEKSPGKLLVKMPFQASPGGKGEGGGATTSAQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHAESPKAPMPLLPPPPPPEPQSSEDPISPPEPQDLSSSICKEEKMPRAGSLESDGCPKEPAKTQPMVAAAATTTTTTTTTVAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 9** entries
Position	GlyTouCan ID	Source
49	G49108TO	GlyGen The O-GlcNAc Database
53	G49108TO	GlyGen The O-GlcNAc Database
65	G49108TO	GlyGen The O-GlcNAc Database
134	G49108TO	The O-GlcNAc Database
204	G49108TO	The O-GlcNAc Database
434	G49108TO	GlyGen The O-GlcNAc Database
443	G49108TO	GlyGen The O-GlcNAc Database
444	G49108TO	GlyGen The O-GlcNAc Database
485	G49108TO	GlyGen The O-GlcNAc Database