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Transcription factor E2F1

Summary

UniProt ID

Q01094

Gene Symbol

E2F1
RBBP3

Organism

Homo sapiens (human)

External Links

GlyGen: Q01094
PubChem: Q01094
The O-GlcNAc Database: Q01094

Annotation

Keyword

3D-structure
Acetylation
Activator
Apoptosis
Cell cycle
DNA-binding
Host-virus interaction
Methylation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation

Gene Ontology (GO)

Displaying entries **1 - 10** of 23 in total

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GO Term
forebrain development
positive regulation of apoptotic process
negative regulation of DNA binding
negative regulation of fat cell differentiation
positive regulation of fibroblast proliferation
negative regulation of fat cell proliferation
lens fiber cell apoptotic process
anoikis
mRNA stabilization
intrinsic apoptotic signaling pathway by p53 class mediator

Displaying **all 8** entries
GO Term
chromatin
nucleus
cytoplasm
protein-containing complex
nucleoplasm
centrosome
RNA polymerase II transcription regulator complex
Rb-E2F complex

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GO Term
DNA binding
molecular adaptor activity
DNA-binding transcription factor binding
protein dimerization activity
DNA-binding transcription factor activity, RNA polymerase II-specific
DNA-binding transcription activator activity
DNA-binding transcription factor activity
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding

Annotation information from UniProt.

Sequence

MALAGAPAGGPCAPALEALLGAGALRLLDSSQIVIISAAQDASAPPAPTGPAAPAAGPCDPDLLLFATPQAPRPTPSAPRPALGRPPVKRRLDLETDHQYLAESSGPARGRGRHPGKGVKSPGEKSRYETSLNLTTKRFLELLSHSADGVVDLNWAAEVLKVQKRRIYDITNVLEGIQLIAKKSKNHIQWLGSHTTVGVGGRLEGLTQDLRQLQESEQQLDHLMNICTTQLRLLSEDTDSQRLAYVTCQDLRSIADPAEQMVMVIKAPPETQLQAVDSSENFQISLKSKQGPIDVFLCPEETVGGISPGKTPSQEVTSEEENRATDSATIVSPPPSSPPSSLTTDPSQSLLSLEQEPLLSRMGSLRAPVDEDRLSPLVAADSLLEHVREDFSGLLPEEFISLSPPHEALDYHFGLEEGEGIRDLFDCDFGDLTPLDF

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
382			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **11 - 17** of 17 in total

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Pathway Name	Organism
Oxidative Stress Induced Senescence	Homo sapiens
Pre-NOTCH Transcription and Translation	Homo sapiens
TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	Homo sapiens
Transcription of E2F targets under negative control by DREAM complex	Homo sapiens
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1	Homo sapiens
Transcriptional Regulation by E2F6	Homo sapiens
Transcriptional regulation of granulopoiesis	Homo sapiens