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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Decorin
Summary
- UniProt ID
- Q01129
- Gene Symbol
-
- Dcn
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Direct protein sequencing
- Disulfide bond
- Extracellular matrix
- Leucine-rich repeat
- Proteoglycan
- Reference proteome
- Repeat
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of macroautophagy |
| negative regulation of angiogenesis |
| positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
| positive regulation of mitochondrial depolarization |
| GO Term |
|---|
| extracellular space |
| collagen type VI trimer |
| GO Term |
|---|
| collagen binding |
| glycosaminoglycan binding |
| extracellular matrix binding |
Sequence
MKATLVLFLLAQVSWAGPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWEFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNHLKELPEKLPKTLQELRLHDNEITKLKKSVFNGLNRMIVIELGGNPLKNSGIENGALQGMKGLGYIRISDTNITAIPQGLPTSISELHLDGNKIAKVDAASLKGMSNLSKLGLSFNSITVVENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYVQVVYLHNNNISEVGQHDFCLPSYQTRKTSYTAVSLYSNPVRYWQIHPHTFRCVFGRSTIQLGNYK
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 34 | O-linked (Xyl...) (glycosaminoglycan) serine |
|
||
| 206 | N-linked (GlcNAc...) asparagine |
|
||
| 241 | N-linked (GlcNAc...) asparagine |
|
||
| 257 | N-linked (GlcNAc...) asparagine |
|
||
| 298 | N-linked (GlcNAc...) asparagine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| A tetrasaccharide linker sequence is required for GAG synthesis | Rattus norvegicus |
| CS/DS degradation | Rattus norvegicus |
| Chondroitin sulfate biosynthesis | Rattus norvegicus |
| Degradation of the extracellular matrix | Rattus norvegicus |
| Dermatan sulfate biosynthesis | Rattus norvegicus |
| ECM proteoglycans | Rattus norvegicus |
