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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Proheparin-binding EGF-like growth factor
Summary
- UniProt ID
- Q01580
- Gene Symbol
-
- HBEGF
- DTR
- HEGFL
- Organism
- Sus scrofa (pig)
External Links
- PubChem
- Q01580
Annotation
- Keyword
-
- Cell membrane
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Growth factor
- Heparin-binding
- Reference proteome
- Secreted
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| positive regulation of cell population proliferation |
| epidermal growth factor receptor signaling pathway |
| GO Term |
|---|
| extracellular space |
| plasma membrane |
| GO Term |
|---|
| heparin binding |
| epidermal growth factor receptor binding |
| growth factor activity |
Sequence
MKLLPSVVLKLFLAAVFSALVTGESLERLRRGLADGTSNLVSPTESTDQLLPPGGGRGREVLDLEEADLDLLRADFSSKPQALATPSKEERGKRKKKGKGLGKKRDPCLRKYKDFCIHGECKYVKELRAPSCICHPGYHGERCHGLSLPVKNRLYTYDHTTILAVVAVVLSSVCLLVIVGLLMFRYHRRGGYDVENEEKVKLGVTASH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 85 | O-linked (GalNAc...) threonine |
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Cargo recognition for clathrin-mediated endocytosis | Sus scrofa |
| Clathrin-mediated endocytosis | Sus scrofa |
| Downregulation of ERBB2 signaling | Sus scrofa |
| EGFR Transactivation by Gastrin | Sus scrofa |
| EGFR downregulation | Sus scrofa |
| EGFR interacts with phospholipase C-gamma | Sus scrofa |
| ERBB2 Activates PTK6 Signaling | Sus scrofa |
| ERBB2 Regulates Cell Motility | Sus scrofa |
| Extra-nuclear estrogen signaling | Sus scrofa |
| GAB1 signalosome | Sus scrofa |
