Downregulation of ERBB2 signaling

Summary
Species
Sus scrofa
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ERBB2:ERBIN:HSP90:CDC37Ub-ERBB2:ERBIN:Ub-HSP90:CDC37UbUb-ERBB2:ERBIN:HSP90:CDC37MATKp-ERBB2 heterodimers:MATKp-ERBB2 heterodimersH2OPiPhosphorylated ERBB2 heterodimersPhosphorylated ERBB2:EGFR heterodimersPhosphorylated ERBB2:EGFR heterodimers:PTPN18PTPN18Phosphorylated ERBB2(dephosphorylated at Y1196,Y1112 and Y1248):EGFR heterodimers:PTPN18
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying 1 entry
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q01580 Proheparin-binding EGF-like growth factor
  • DTR
  • HBEGF
  • HEGFL
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025