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Dual specificity mitogen-activated protein kinase kinase 1

Summary

UniProt ID

Q01986

Gene Symbol

Map2k1
Mek1
Prkmk1

Organism

Rattus norvegicus (Norway rat)

External Links

GlyGen: Q01986
PubChem: Q01986
The O-GlcNAc Database: Q01986

Annotation

Keyword

ATP-binding
Cytoskeleton
Direct protein sequencing
Membrane
Nucleus
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Tyrosine-protein kinase

Gene Ontology (GO)

Displaying entries **1 - 10** of 56 in total

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GO Term
cellular senescence
type B pancreatic cell proliferation
positive regulation of muscle contraction
vesicle transport along microtubule
Golgi inheritance
thymus development
positive regulation of axonogenesis
response to glucocorticoid
Bergmann glial cell differentiation
face development

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GO Term
glutamatergic synapse
perikaryon
mitochondrion
cytosol
endoplasmic reticulum
centrosome
early endosome
late endosome
focal adhesion
postsynaptic density

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GO Term
protein serine/threonine kinase activity
protein tyrosine kinase activity
protein-containing complex binding
protein kinase binding
protein kinase activator activity
scaffold protein binding
protein serine kinase activity
protein serine/threonine kinase activator activity
mitogen-activated protein kinase kinase kinase binding
MAP kinase kinase activity

Annotation information from UniProt.

Sequence

MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAASI

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying 1 entry
Position	Description	PubMed ID	GlyTouCan ID	Source
			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Frs2-mediated activation	Rattus norvegicus
MAP2K and MAPK activation	Rattus norvegicus
MAPK3 (ERK1) activation	Rattus norvegicus
Negative feedback regulation of MAPK pathway	Rattus norvegicus
RAF activation	Rattus norvegicus
Signal transduction by L1	Rattus norvegicus