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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Dual specificity mitogen-activated protein kinase kinase 1
Summary
- UniProt ID
- Q01986
- Gene Symbol
-
- Map2k1
- Mek1
- Prkmk1
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- ATP-binding
- Cytoskeleton
- Direct protein sequencing
- Membrane
- Nucleus
- Phosphoprotein
- Reference proteome
- Serine/threonine-protein kinase
- Tyrosine-protein kinase
- Gene Ontology (GO)
| GO Term |
|---|
| perinuclear region of cytoplasm |
| nucleus |
| Golgi apparatus |
| cell cortex |
| membrane |
| axon |
| dendrite |
| dendrite cytoplasm |
| GO Term |
|---|
| protein serine/threonine/tyrosine kinase activity |
| MAP-kinase scaffold activity |
| ATP binding |
| small GTPase binding |
Sequence
MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELLFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAASI
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
|
|
G49108TO
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Frs2-mediated activation | Rattus norvegicus |
| MAP2K and MAPK activation | Rattus norvegicus |
| MAPK3 (ERK1) activation | Rattus norvegicus |
| Negative feedback regulation of MAPK pathway | Rattus norvegicus |
| RAF activation | Rattus norvegicus |
| Signal transduction by L1 | Rattus norvegicus |
